Modulation of the expression of integrins on glial cells during experimental autoimmune encephalomyelitis. A central role for TNF-alpha.

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2014 • 14,293 citations

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1992 • 9,986 citations

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue.

1980 • 3,822 citations

Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin

1992 • 1,711 citations

Transferrin receptor on endothelium of brain capillaries

1984 • 1,008 citations

Cytokines and the nervous system II: actions and mechanisms of action

1995 • 928 citations

The adhesion molecule and cytokine profile of multiple sclerosis lesions

1995 • 761 citations

Cytokines in inflammatory brain lesions: helpful and harmful

1996 • 727 citations

Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery.

1992 • 627 citations

Integrin transmembrane signaling and cytoskeletal control

1995 • 616 citations

Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor.

1990 • 548 citations

Vitronectin and its receptors

1993 • 406 citations

Collagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by alpha 1 beta 1 and alpha 2 beta 1 integrins.

1995 • 399 citations

Matrix Metalloproteinases in the Normal Human Central Nervous System, Microglial Nodules, and Multiple Sclerosis Lesions

1996 • 290 citations

Integrin α2β1 Is a Positive Regulator of Collagenase (MMP-1) and Collagen α1(I) Gene Expression

1995 • 281 citations

The induction of intercellular adhesion molecule 1 (ICAM-1) expression on human fetal astrocytes by interferon-λ, tumor necrosis factor α, lymphotoxin, and interleukin-1: relevance to intracerebral antigen presentation

1989 • 227 citations

Characterization of integrin receptors in normal and neoplastic human brain.

1993 • 221 citations

Animal models of human disease Experimental autoimmune encephalomyelitis in rodents as a model for human demyelinating disease

1995 • 218 citations

A developmental analysis of oligodendroglial integrins in primary cells: changes in αv-associated β subunits during differentiation

1994 • 209 citations

A monoclonal antibody to α4 integrin suppresses and reverses active experimental allergic encephalomyelitis

1995 • 206 citations

Transient functional expression of alphaVbeta 3 on vascular cells during wound repair.

1996 • 203 citations

The intracellular functions of alpha6beta4 integrin are regulated by EGF.

1996 • 188 citations

Inhibition of experimental autoimmune encephalomyelitis by an antibody to the intercellular adhesion molecule ICAM‐1

1993 • 186 citations

The cell surface metalloprotease/disintegrin Kuzbanian is required for axonal extension in Drosophila

1996 • 183 citations

Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor α and tumor necrosis factor β

1995 • 179 citations

Reversible Inhibitory Effects of Interferon‐γ and Tumour Necrosis Factor‐α on Oligodendroglial Lineage Cell Proliferation and Differentiation In Vitro

1996 • 162 citations

Pathology, histochemistry and immunocytochemistry of lesions in acute multiple sclerosis

1989 • 160 citations

Expression of beta 1 integrins in sensory neurons of the dorsal root ganglion and their functions in neurite outgrowth on two laminin isoforms

1993 • 155 citations

Adhesion-related molecules in the central nervous system. Upregulation correlates with inflammatory cell influx during relapsing experimental autoimmune encephalomyelitis.

1991 • 128 citations

Anti‐β1 integrin antibody inhibits schwann cell meylination

1994 • 116 citations

[31] Myelin basic proteins

1974 • 111 citations

Tumor necrosis factor alpha induces adhesion molecule expression on human fetal astrocytes.

1992 • 98 citations

α_v Integrin subunit is predominantly located in nervous tissue and skeletal muscle during mouse development

1994 • 96 citations

The vitronectin receptor serves as an accessory molecule for the activation of a subset of gamma/delta T cells.

1991 • 93 citations

Bone matrix constituents stimulate interleukin-1 release from human blood mononuclear cells.

1991 • 84 citations

Vitronectin and Integrin Vitronectin Receptor Localization in Multiple Sclerosis Lesions

1995 • 75 citations

Anatomical Localization of β1 Integrin-like Immunoreactivity in Rat Brain

1993 • 66 citations

Expression and distribution of functional intergrins in rat CNS glia

1994 • 63 citations

Distribution of Integrin-like Immunoreactivity on Primate Brain Microvasculature

1996 • 56 citations

Beta 1 integrin-mediated interaction with extracellular matrix proteins regulates cytokine gene expression in synovial fluid cells of rheumatoid arthritis patients.

1993 • 55 citations

Expression of a beta 1-related integrin by oligodendroglia in primary culture: evidence for a functional role in myelination

1994 • 51 citations

Myelin-induced experimental allergic encephalomyelitis in Lewis rats: tumor necrosis factor α levels in serum and cerebrospinal fluid Immunohistochemical expression in glial cells and macrophages of optic nerve and spinal cord

1996 • 46 citations

The level of tumor necrosis factor-α producing cells in the spinal cord correlates with the degree of Theiler's murine encephalomyelitis virus-induced demyelinating disease

1996 • 45 citations

α6β4 and α6β1 Integrins in Astrocytomas and Other CNS Tumors

1996 • 40 citations

Immunostaining of human brain capillaries by antibodies to very late antigens

1990 • 37 citations

Analysis of integrin expression on oligodendrocytes during axo-glial interaction by using rat-mouse xenocultures

1996 • 36 citations

Antigen-independent, integrin-mediated T cell activation.

1995 • 35 citations

Tumour necrosis factor alpha is elevated in serum and cerebrospinal fluid in multiple sclerosis and inflammatory neuropathies

1996 • 23 citations

Interactions of Migrating T Lymphocytes, Inflammatory Mediators, and the Extracellular Matrix

1995 • 19 citations

Localization of vitronectin- and fibronectin-receptors on cultured human glioma cells

1994 • 15 citations

Regulation of cytokine gene expression in experimental autoimmune encephalomyelitis

1996 • 9 citations