Nonspecific Immunoregulation by Macrophages and Their Products

A rapid method for the isolation of functional thymus‐derived murine lymphocytes

1973 • 4,203 citations

IMMUNIZATION OF DISSOCIATED SPLEEN CELL CULTURES FROM NORMAL MICE

1967 • 2,062 citations

POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS

1972 • 921 citations

POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS

1972 • 742 citations

T Cell Control of Antibody Production

1974 • 582 citations

Das Verhalten der kutanen Tuberkulinreaktion während der Masern

1908 • 337 citations

EVIDENCE OF SUPPRESSOR CELL ACTIVITY IN SPLEENS OF MICE BEARING PRIMARY TUMORS INDUCED BY MOLONEY SARCOMA VIRUS

1974 • 325 citations

Heterocytolysis by Macrophages Activated by Bacillus Calmette-Gurin: Lysosome Exocytosis into Tumor Cells

1974 • 278 citations

INHIBITORY AND STIMULATORY EFFECTS OF CONCANAVALIN A ON THE RESPONSE OF MOUSE SPLEEN CELL SUSPENSIONS TO ANTIGEN

1972 • 275 citations

THE EFFECTS OF MERCAPTOETHANOL AND OF PERITONEAL MACROPHAGES ON THE ANTIBODY-FORMING CAPACITY OF NONADHERENT MOUSE SPLEEN CELLS IN VITRO

1972 • 267 citations

Macrophage-Lymphocyte Interaction in the Antigen-Induced Blastogenic Response of Human Peripheral Blood Leukocytes

1968 • 263 citations

The Transformation of Column-Purified Lymphocytes with Nonspecific and Specific Antigenic Stimuli

1968 • 243 citations

Biological expressions of lymphocyte activation. 3. Suppression of plaque-forming cell responses in vitro by supernatant fluids from concanavalin A-activated spleen cell cultures.

1974 • 235 citations

ACTIVATION OF T AND B LYMPHOCYTES IN VITRO

1974 • 231 citations

PROMOTION OF REPLICATION IN LYMPHOID CELLS BY SPECIFIC THIOLS AND DISULFIDES IN VITRO

1973 • 225 citations

Depression of Cell-Mediated Immunity during Acute Infectious Mononucleosis

1974 • 214 citations

Biological effects of the adjuvant Corynebacterium parvum

1972 • 205 citations

Inhibition of Proliferation of Lymphoma Cells and T Lymphocytes by Suppressor Cells from Spleens of Tumor-Bearing Mice

1975 • 190 citations

The splenic suppressor cell. I. Activity of thymus-dependent adherent cells: changes with age and stress.

1974 • 188 citations

Lymphocyte reactivity in vitro

1970 • 182 citations

Biological effects of the adjuvant Corynebacterium parvum

1972 • 181 citations

Immune responses in vitro

1972 • 168 citations

Enhancement of antibody synthesis in vitro by mercaptoethanol

1972 • 160 citations

Production by Stimulated Macrophages of Factors depressing Lymphocyte Transformation

1973 • 160 citations

Immune Response Restoration with Macrophage Culture Supernatants

1971 • 155 citations

“Spontaneous” B cell activation due to loss of normal mouse serum suppressor

1972 • 155 citations

An Inhibitor of Cell Proliferation Released by Cultures of Macrophages

1974 • 151 citations

The interaction of human macrophages and lymphocytes in the phytohemagglutinin-stimulated production of interferon

1971 • 148 citations

Studies of Immune Mechanisms in Leprosy

1968 • 143 citations

STIMULATION OF NATURAL IMMUNITY TO ESCHERICHIA COLI INFECTIONS OBSERVATIONS ON MICE

1955 • 143 citations

Lymphocyte reactivity in vitro

1970 • 142 citations

Regulation of lymphocyte responses in vitro. 3. Inhibition by adherent cells of the T-lymphocyte response to phytohemagglutinin.

1973 • 141 citations

Enhancement by Reducing Agents of the Transformation of Human and Rabbit Peripheral Lymphocytes

1970 • 141 citations

In vitro inhibition of tumour cell growth and DNA synthesis by peritoneal and lung macrophages from mice injected with corynebacterium parvum

1974 • 139 citations

Immunosuppression in murine malaria. I. General characteristics.

1971 • 139 citations

THE INTERACTION OF HUMAN MONOCYTES AND LYMPHOCYTES

1968 • 139 citations

The Effect of Immunoregulatory α Globulin (IRA) upon Lymphocytes in Vitro

1972 • 135 citations

Immunity to murine sarcoma virus-inducted tumors. II. Suppression of T cell-mediated immunity by cells from progressor animals.

1974 • 134 citations

The requirement for macrophages in the in vitro immune response

1971 • 134 citations

INHIBITORY AND STIMULATORY EFFECTS OF CONCANAVALIN A ON THE RESPONSE OF MOUSE SPLEEN CELL SUSPENSIONS TO ANTIGEN

1973 • 133 citations

Antigenic Competition: A Review of Nonspecific Antigen-Induced Suppression

1974 • 128 citations

Macrophage regulation of DNA synthesis in lymphoid cells: Effects of a soluble factor from macrophages

1973 • 125 citations

THE PRIMARY IMMUNE RESPONSE IN MICE

1968 • 124 citations

Biological Expressions of Lymphocyte Activation

1974 • 124 citations

Potentiation of Cultured Mouse Thymocyte Responses by Factors Released by Peripheral Leucocytes

1971 • 124 citations

Potentiation of the T lymphocyte response to mitogens

1974 • 122 citations

The Splenic Suppressor Cell

1974 • 113 citations

The splenic suppressor cell. II. Suppression of mixed lymphocyte reaction by thymus-dependent adherent cells.

1974 • 111 citations

MECHANISM OF ACTIVATION OF THE BONE MARROW-DERIVED LYMPHOCYTE

1973 • 111 citations

REGULATION OF LYMPHOCYTE RESPONSES IN VITRO

1972 • 110 citations

Regulation of lymphocyte responses in vitro,

1973 • 110 citations

THE EFFECT OF 2-MERCAPTOETHANOL ON MURINE MIXED LYMPHOCYTE CULTURES

1974 • 107 citations

Inhibition of Spleen Cell DNA Synthesis by Autologous Macrophages

1966 • 105 citations

Possibilities and Problems of Immunologic Intervention in Cancer

1972 • 104 citations

Enhancement of the Humoral Response of T Cell-Depleted Murine Spleens by a Factor Derived from Human Monocytes in Vitro

1974 • 94 citations

HUMAN MONOCYTES AND MACROPHAGES

1970 • 93 citations

Nonspecific Resistance to Infections

1959 • 92 citations

Macrophages in the mixed leukocyte culture reaction (MLC)

1974 • 90 citations

The Suppressive Role of Mouse Peritoneal Phagocytes in Agglutinin Response

1965 • 90 citations

Immunity to Murine Sarcoma Virus-Induced Tumors

1974 • 90 citations

IMMUNOLOGIC INCOMPETENCE OF IMMUNOLOGICALLY RUNTED ANIMALS

1964 • 87 citations

On the Mode of Action of BCG

1973 • 82 citations

Immunocytology of cultured IgM-forming cells of mouse. I. Requirement of phagocytic cell factor for the growth of IgM-forming tumor cells in tissue culture.

1972 • 81 citations

Induction of Immunity and Tolerance in vitro in the Absence of Phagocytic Cells

1970 • 80 citations

Depression of the tuberculin reaction by attenuated measles virus vaccine.

1963 • 79 citations

Immunosuppression During Influenza Virus Infection

1974 • 79 citations

INCREASED ANTIBACTERIAL RESISTANCE AND IMMUNODEPRESSION DURING GRAFT-VERSUS-HOST REACTIONS IN MICE

1969 • 78 citations

Mechanisms by which activated normal macrophages destroy syngeneic rat tumour cells in vitro. Cytokinetics, non-involvement of T lymphocytes, and effect of metabolic inhibitors.

1974 • 77 citations

Immune responses in vitro. X. Functions of macrophages.

1974 • 77 citations

The growth of tumours in T-cell deprived mice and their response to treatment withCorynebacterium parvum

1973 • 76 citations

The role of humoral factors in the initiation of in vitro primary immune responses. 3. Characterization of factors that replace thymus-derived cells.

1973 • 75 citations

Antigenic Competition

1973 • 73 citations

Regulation of Lymphocyte Responses in Vitro

1973 • 72 citations

Effect of the graft-versus-host reaction on the immunological responsiveness of the mouse

1961 • 70 citations

Effect of allogeneic cell interaction on the primary immune response in vitro. Cell types involved in suppression and stimulation of antibody synthesis.

1972 • 66 citations

The Splenic Suppressor Cell

1974 • 65 citations

Suppression of in vitro lymphocyte stimulation in mice bearing primary moloney sarcoma virus-induced tumors

1974 • 64 citations

Reconstitution of the Antibody Response in Vitro of T Cell-Deprived Spleen Cells by Supernatants from Spleen Cell Cultures

1972 • 64 citations

Activation of Guinea Pig Macrophages by Bacterial Lipopolysaccharide Requires Bone Marrow-Derived Lymphocytes

1975 • 64 citations

Immunological significance of changes in lymph nodes across the leprosy spectrum.

1971 • 62 citations

Studies of an inhibitor of DNA synthesis and a nonspecific mitogen elaborated by human lymphoblasts.

1970 • 60 citations

Immune Responses in Vitro

1974 • 57 citations

Effect of normal mouse serum on mouse lymphocyte transformation in vitro

1974 • 56 citations

Mode of Action of a Supernatant Activity from T-Cell Cultures that Nonspecifically Stimulates the Humoral Immune Response

1974 • 54 citations

Suppression of Cell-Mediated Immunity in Experimental African Trypanosomiasis

1974 • 54 citations

Alternative potentiating and inhibitory effects of GVH reaction on formation of antibodies against a thymus-independent polysaccharide (S3).

1973 • 51 citations

Immune Response Suppression by an Inhibitor in Normal and Immune Mouse Serum

1972 • 51 citations

Steroid Sensitivity of the Response of Human Lymphocytes to Phytohemagglutinin and Pokeweed Mitogen: Role of Phagocytic Cells

1974 • 49 citations

The Third Cell Type Required for the Immune Response of Spleen Cells in vitro

1971 • 49 citations

Cell-Mediated Immunity in Humans During Viral Infection I. Effect of Rubella on Dermal Hypersensitivity, Phytohemagglutinin Response, and T Lymphocyte Numbers

1974 • 48 citations

The Role of Humoral Factors in the Initiation of in Vitro Primary Immune Responses

1973 • 48 citations

Phytohaemagglutinin-induced lymphocyte transformation in leprosy.

1971 • 48 citations

EVIDENCE FOR A CYTOLYTIC FACTOR RELEASED BY MACROPHAGES

1974 • 48 citations

CONCOMITANT IMMUNITY TO SYNGENEIC METHYLCHOLANTHRENE INDUCED TUMOURS IN MICE. OCCURRENCE AND SPECIFICITY OF CONCOMITANT IMMUNITY

1973 • 47 citations

Soluble mediators of t‐b interaction

1973 • 46 citations

Immunocytology of Cultured IgM-Forming Cells of Mouse

1972 • 46 citations

Cellular basis for the immune response to methylcholanthrene‐induced tumors in mice. Heterogeneity of effector cells

1975 • 44 citations

Immunological parameters of host-tumor relationships

1971 • 44 citations

Alternative Potentiating and Inhibitory Effects of GVH Reaction on Formation of Antibodies Against a Thymus-Independent Polysaccharide (SIII)

1973 • 43 citations

Effect of macrophages on periodate-induced transformation of normal and chronic lymphatic leukaemia lymphocytes.

1974 • 41 citations

Enhancement and depression of the antibody response in mice caused by Corynebacterium parvum.

1974 • 40 citations

Regulation of antibody response in vitro. 8. Multiplicity of soluble factors released from carrier-specific cells.

1974 • 38 citations

The stimulatory effect of tumor bearing upon the T- and B-cell subpopulations of the mouse spleen.

1973 • 38 citations

Specific inhibition of lymphocyte blastogenic responses to mitogens by a factor produced by cultured human malignant lymphoma cells.

1974 • 37 citations

Normal Immunosuppressive Protein (N.I.P.)

1973 • 35 citations

Studies on the effect of macrophages in an in vitro graft reaction system.

1971 • 34 citations

Role of Monocytes in the Mixed Leukocyte Culture Reaction

1968 • 34 citations

Immunological Induction of DNA Synthesis in Mouse Peritoneal Macrophages

1973 • 32 citations

Enhancement of Mouse Thymus Cells Response to Periodate Treatment by a Soluble Factor

1972 • 30 citations

Inhibition of in vitro lymphocyte blastogenesis by inhibitor produced by cultured human lymphoblasts.

1974 • 29 citations

Reconstitution of immunocompetence in B cells by addition of concanavalin A or concanavalin A-treated thymus cells.

1973 • 27 citations

Role of a non-committed accessory cell in the in vivo suppression of a syngeneic tumour by immune lymphocytes.

1975 • 25 citations

Antigen-Induced Blastogenesis: The Human Cell Determining the Specificity of Response in Vitro

1970 • 25 citations

Macrophage dependent protection of tumour cells.

1973 • 25 citations

Regulation of Antibody Response in Vitro

1974 • 24 citations

Detection of cytotoxic T lymphocytes in the EL4 mouse leukemia system: Increased activity of immune spleen and peritoneal cells following preincubation and cell fractionation procedures

1974 • 21 citations

The stimulatory effects of bearing primary methylcholanthrene‐induced tumors upon the murine lymphoreticular system

1973 • 20 citations

Mechanisms of target cell destruction by alloimmune peritoneal macrophages. I. The effect of treatment with sodium fluoride.

1971 • 19 citations

The role of humoral factors in the initiation of in vitro primary immune responses. IV. Are macrophages the adherent cell type required for cell cooperation.

1974 • 18 citations

Presence of a reversible inhibitor(s) for human lymphoid cell RNA, protein, and DNA synthesis in the extracts of established human lymphoid cell lines

1974 • 18 citations

Immunotherapy of Human Cancer (Part 1 of 3)

1973 • 16 citations

The Production of Proliferation Inhibitory Factor (PIF) by Mouse Spleen Cells in Vitro

1974 • 16 citations

The Role of Humoral Factors in the Initiation of in Vitro Primary Immune Responses

1974 • 15 citations

Mouse Spleen Cells Cultivated in Homologous Serum Can Make Primary Antibodies in Vitro Provided the T‐Cells Are Non‐Specifically Activated

1972 • 13 citations

The lymphocyte response to primary moloney sarcoma virus tumors: Definition of a non‐specific component of the in vitro cellular hyporeactivity of tumor‐bearing hosts

1974 • 13 citations

Unmasking and Functional Characterization of T ‐Cell‐Replacing Factors Obtained from Super‐natants of Allogeneic Spleen Cell Mixtures

1974 • 12 citations

SPECIFIC HETEROLOGOUS ENHANCEMENT OF IMMUNE RESPONSES

1974 • 12 citations

Nonspecific cytotoxicity of spleen cells and the specific cytotoxic action of thymus-derived lymphocytes in vitro

1974 • 9 citations

Effect of Locally Administered Endotoxin on Regenerating Appendix Structure and Responses of Appendix Cells to Mitogens

1973 • 7 citations

Sensitivity of non-human cells to human lymphocyte 'proliferation inhibitory factor' (PIF) in vitro.

1973 • 5 citations