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Central α-adrenergic systems as targets for hypotensive drugs

Data up to Jan 2025

Published1978
Citations514
References214

Total Citations Per Year

Abstract

References (214)

Stereotaxic Mapping of the Monoamine Pathways in the Rat Brain*

1971 • 3,816 citations

A STUDY OF THE ADRENOTROPIC RECEPTORS

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Ascending Monoamine Neurons to the Telencephalon and Diencephalon

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Inhibition of both noradrenergic and serotonergic neurons in brain by the α-adrenergic agonist clonidine

1975 • 1,010 citations

The inhibitory action of noradrenaline and adrenaline on acetylcholine output by guinea‐pig ileum longitudinal muscle strip

1969 • 698 citations

Reflexogenic Areas of the Cardiovascular System

1960 • 695 citations

Evidence for a central noradrenaline receptor stimulation by clonidine

1970 • 550 citations

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1962 • 531 citations

Relative pre- and postsynaptic potencies of ?-adrenoceptor agonists in the rabbit pulmonary artery

1975 • 455 citations

Drug‐Induced Changes in the Release of 3H‐Monoamines from Field Stimulated Rat Brain Slices

1971 • 453 citations

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1976 • 451 citations

Integrative neural cardiovascular control.

1971 • 437 citations

Reflexogenic Areas of the Cardiovascular System

1958 • 430 citations

Supersensitivity and subsensitivity to sympathomimetic amines.

1963 • 412 citations

Different alpha-adrenoreceptors in the central nervous system mediating biochemical and functional effects of clonidine and receptor blocking agents

1976 • 378 citations

TONIC AND REFLEX FUNCTIONS OF MEDULLARY SYMPATHETIC CARDIOVASCULAR CENTERS

1946 • 368 citations

Catecholamine receptor agonists

1976 • 318 citations

Comparison of the effects of clonidine on pre-and postsynaptic adrenoceptors in the rabbit pulmonary artery

1974 • 316 citations

Degeneration studies of primary afferents of IXth and Xth cranial nerves in the cat

1964 • 316 citations

Alpha sympathomimetic inhibition of adrenergic and cholinergic transmission in the rabbit heart

1972 • 293 citations

Clinical pharmacology and pharmacokinetics of clonidine

1976 • 275 citations

Hypertension: Mechanisms and Management

1978 • 270 citations

Evidence for an α-sympathomimetic component in the effects of catapresan on vasomotor centres: Antagonism by piperoxane

1971 • 268 citations

Handbook of Physiology. Section 1: Neurophysiology

1961 • 260 citations

Decarboxylase Inhibition and Blood Pressure Reduction by α-Methyl-3,4-Dihydroxy-DL-phenylalanine

1960 • 254 citations

Distribution of carotid sinus and depressor nerves in cat brain stem

1968 • 244 citations

The localization of the first synapse in the carotid sinus baroreceptor reflex pathway and its alteration of the afferent input

1969 • 234 citations

Investigations into the mechanism of the hypotensive effect of 2-(2,6-dichlorphenylamino)-2-imidazoline-HCl

1967 • 225 citations

Evidence for Adrenaline Neurons in the Rat Brain

1973 • 219 citations

Involvement of α-receptors in clonidine-induced inhibition of transmitter release from central monoamine neurones

1973 • 202 citations

Clonidine-induced inhibition of sympathetic nerve activity: No indication for a central presynaptic or an indirect sympathomimetic mode of action

1974 • 200 citations

Handbook of Physiology

1960 • 190 citations

Possible involvement of central adrenaline neurons in vasomotor and respiratory control. Studies with clonidine and its interactions with piperoxane and yohimbine

1974 • 184 citations

Localization of the hypotensive effect of 2-(2-6-dichlorophenylamino)-2-imidazoline hydrochloride (St 155, catapresan)

1969 • 174 citations

Studies on catecholamines, renin and aldosterone following catapresan® (2-(2,6-dichlor-phenylamine)-2-imidazoline hydrochloride) in hypertensive patients

1970 • 169 citations

Preganglionic sympathetic activity in normal and in reserpine‐treated cats

1960 • 169 citations

Inhibition of dopa decarboxylase by the hydrazino analog of α-methyldopa

1962 • 166 citations

Role of Central and Peripheral Adrenergic Mechanisms in Neurogenic Hypertension Produced by Brainstem Lesions in Rat

1974 • 163 citations

Acute hypotensive action of 2-(2,6-dichlorophenylamino)- 2-imidazoline hydrochloride (St 155) after infusion into the cat's vertebral artery

1967 • 163 citations

Centrally mediated decrease in sympathetic tone induced by 2(2,6-dichlorophenylamino)-2 imidazoline (S.T. 155, Catapresan)

1967 • 154 citations

Cardiovascular effects of 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride (ST 115)

1968 • 147 citations

Clinical and Chemical Studies with α -Methyl-Dopa in Patients with Hypertension

1962 • 146 citations

Participation of Central Noradrenergic Neurons in Arterial Baroreceptor Reflexes in the Rabbit

1971 • 145 citations

The sinus nerve and baroreceptor input to the medulla of the cat.

1975 • 139 citations

Action of -adrenergic blocking drugs on the sympathetic centres and their interactions with the central sympatho-inhibitory effect of clonidine.

1973 • 135 citations

Different types of sympathomimetic α-receptors

1965 • 129 citations

Activation of the central pathway of the baroreceptor reflex, a possible mechanism of the hypotensive action of clonidine

1973 • 127 citations

Release by sympathetic stimulation of α-methylnoradrenaline stored in the heart after administration of α-methyldopa

1963 • 125 citations

Participation of Central Noradrenergic Neurons in Arterial Baroreceptor Reflexes in the Rabbit: A STUDY WITH INTRACISTERNALLY ADMINISTERED 6-HYDROXYDOPAMINE

1972 • 124 citations

Antihypertensive Effect of Clonidine

1971 • 121 citations

Localization of the central cardiovascular action of clonidine

1973 • 120 citations

Central action of drugs in blood pressure regulation

1977 • 120 citations

�ber den Wirkungsmechanismus einer neuen antihypertensiven Substanz mit Imidazolinstruktur

1967 • 117 citations

Evidence that punctate intracerebral administration of 6-hydroxydopamine fails to produce selective neuronal degeneration

1974 • 111 citations

Centrally induced reduction in sympathetic tone — A postsynaptic α-adrenoceptor-stimulating action of imidazolines

1976 • 110 citations

CENTRAL ACTION OF DRUGS IN BLOOD PRESSURE REGULATION

1977 • 107 citations

Quantum mechanical study of the conformational properties of phenethylamines of biochemical and medicinal interest

1972 • 105 citations

Cardiovascular effects of 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride (ST 155)

1968 • 105 citations

Cardiovascular regulation by central adrenergic mechanisms and its alteration by hypotensive drugs.

1975 • 105 citations

Some biochemical effects of alpha-methyl-3,4-dihydroxyphenylalanine and related compounds in mice.

1961 • 104 citations

Pharmacodynamic Effects of a New Antihypertensive Drug, Catapres (ST-155)

1969 • 104 citations

Central hypotensive effect of α-methyldopa

1968 • 103 citations

Hypothalamic alpha adrenergic receptors in cardiovascular regulation

1974 • 103 citations

Analysis of the cardiovascular effects of 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride (Catapres)

1968 • 101 citations

Role of noradrenaline and serotonin in the central control of blood pressure in normotensive and spontaneously hypertensive rats.

1975 • 100 citations

Effect of duration and frequency of stimulation on the presynaptic inhibition by ?-adrenoceptor stimulation of the adrenergic transmission

1973 • 99 citations

Facilitation of vagal reflex bradycardia by an action of clonidine on central α-receptors

1972 • 98 citations

Effects of clonidine on the baroreceptor-heart rate reflex and on single aortic baroreceptor fibre discharge

1974 • 97 citations

Further evidence for a central hypotensive action of α‐methyldopa in both the rat and cat

1973 • 97 citations

Evidence for a central activation of a vagal cardiodepressor reflex by clonidine

1972 • 96 citations

Noradrenaline: Central inhibitory control of blood pressure and heart rate

1974 • 96 citations

Evidence that the hypotensive action of methyldopa is mediated by central actions of methylnoradrenaline

1971 • 95 citations

A POSSIBLE PHARMACOLOGICAL APPROACH TO MIGRAINE

1969 • 93 citations

Antihypertensive Effect of Clonidine

1971 • 91 citations

SOME OBSERVATIONS ON THE PHARMACOLOGY OF α‐METHYLDOPA

1964 • 89 citations

Central hypotensive effect of α-methyldopa

1967 • 87 citations

α-sympathetic receptor stimulation in the brain and hypotensive activity of α-methyldopa

1972 • 87 citations

Benzo[a]chinolizine, eine neue K�rperklasse mit Wirkung auf den 5-Hydroxytryptamin- und Noradrenalin-Stoffwechsel des Gehirns

1958 • 86 citations

Regulation of blood pressure by the central nervous system

1976 • 83 citations

Pharmacological characterization of B-HT 933 (2-amino-6-ethyl-4,5,7,8-tetrahydro-6H-oxazolo-[5,4-d]-azepindihydrochloride) as a hypotensive agent of the ?Clonidine-type?

1977 • 83 citations

Interactions between 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride (St 155, Catapresan®) and α-adrenergic blocking drugs

1970 • 82 citations

Ability of Serotonin and Norepinephrine to Mimic the Central Effects of Reserpine on Vasomotor Activity

1960 • 82 citations

Increased production of cyclic AMP in gastric tissue by stimulation of histamine2 (H2)-receptors

1973 • 81 citations

The effect of a new decarboxylase inhibitor on endogenous and exogenous monoamines

1963 • 81 citations

Pharmacological actions of the antihypertensive agent N-amidino-2-(2,6-dichlorophenyl)acetamide hydrochloride (BS 100-141).

1975 • 80 citations

Effects of “Diving” on Cardiac Output in Ducks

1967 • 80 citations

Pharmacological studies on the hypotensive effects of clonidine

1971 • 76 citations

Evidence for direct α-adrenoceptor stimulation of effector neurons in cardiovascular centers by clonidine

1974 • 76 citations

Central noradrenergic neurones and the cardiovascular actions of clonidine in the rabbit

1973 • 73 citations

Recent advances in hypertension

1975 • 73 citations

Involvement of adrenergic receptors in central vagus activity

1971 • 71 citations

The central modulatory effect of clonidine on the cardiodepressor reflex after suppression of synthesis and storage of noradrenaline

1975 • 71 citations

Actions of the Decarboxylase Inhibitor, α-Methyl-3,4-dihydroxyphenylalanine, in the Dog

1960 • 71 citations

Investigation into some imidazoline compounds, with respect to peripheral ?-adrenoceptor stimulation and depression of cardiovascular centers

1975 • 71 citations

Effects of adrenergic drugs on pressor responses to hypothalamic stimulation

1973 • 69 citations

The mechanism of the antihypertensive action of α-methyldopa in hypertensive rats

1973 • 69 citations

Zur Pharmakologie von 2-(2,6-Dimethylphenylamino)-4H-5,6-dihydro-1,3-thiazin (Bayer 1470), eines Hemmstoffes adrenergischer und cholinergischer Neurone

1967 • 64 citations

Hemodynamic and vascular responses to antihypertensive treatment with adrenergic blocking agents: A review

1970 • 64 citations

Studies on the centrally mediated hypotensive activity of guanabenz

1976 • 62 citations

Autonomic Nervous System: Newer Mechanisms of Adrenergic Blockade

1966 • 62 citations

Evidence for increased vagal tone and enhancement of baroreceptor reflex activity after xylazine (2-(2,6-dimethylphenylamino)-4-H-5,6-dihydro-1,3-thiazine) in anesthetized dogs

1973 • 62 citations

Effect of the hypotensive drug ST 155 (Catapres) on the heart and peripheral circulation.

1968 • 62 citations

Mechanisms of the pressor and depressor actions of St 155 (2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride, catapres®)

1968 • 61 citations

Effects of phenoxybenzamine, aceperone and clonidine on the level of 3-methoxy-4-hydroxyphenylglycol (MOPEG) in rat brain

1974 • 61 citations

New Class of Antihypertensive Agents

1961 • 60 citations

Effects of clonidine on central sympathetic tone

1970 • 59 citations

CIRCULATORY EFFECTS AT REST AND EXERCISE OF CLONIDINE, AN IMIDAZOLINE DERIVATIVE WITH HYPOTENSIVE PROPERTIES

1969 • 59 citations

Interaction of DOPA Decarboxylase Inhibitors with the Effect of α‐Methyldopa on Blood Pressure and Tissue Monoamines in Rats1

1969 • 59 citations

Amidines and related compounds. 6. Structure-activity relations of antihypertensive and antisecretory agents related to clonidine

1975 • 58 citations

Effects of clonidine and l-dopa on spontaneous and evoked splanchnic nerve discharges

1973 • 57 citations

Release of noradrenaline from the hypothalamus in vivo

1970 • 57 citations

Relationship between activity and structure in derivatives of clonidine.

1975 • 57 citations

Investigation into the positive inotropic effect of clondine in isolated hearts

1974 • 56 citations

Central and peripheral effects of 2-(2,6-dimethylphenylamino)-4-H-5,6-dihydro-1,3-thiazin (Bayer 1470) on the sympathetic system

1970 • 55 citations

Structure activity relationship for central and peripheral alpha adrenergic activities of imidazoline derivatives

1975 • 55 citations

Proceedings: An increased reactivity in hypertensive animals after prolonged antihypertensive therapy.

1974 • 55 citations

Further similarities between the action of clonidine and a central activation of the depressor baroreceptor reflex

1974 • 54 citations

Comparative pharmacodynamics of sympathomimetic imidazolines; studies on intestinal smooth muscle of the rabbit and the cardiovascular system of the cat.

1965 • 54 citations

Effects of clonidine on aortic diameter and aortic baroreceptor activity

1972 • 52 citations

THE CARDIOVASCULAR EFFECTS OF INTRAVENTRICULAR CLONIDINE AND BAY 1470 IN CONSCIOUS HYPERTENSIVE CATS

1974 • 52 citations

Versuch zur Lokalisation des Angriffsortes der Atmungs- und Kreislaufwirkung von Novocain im Liquor cerebrospinalis

1958 • 51 citations

The effect of clonidine and penbutolol, respectively on catecholamines in blood and urine, plasma renin activity and urinary aldosterone in hypertensive patients.

1975 • 50 citations

Mode of action of l-DOPA on central noradrenaline mechanisms

1972 • 50 citations

An involvement of St 155 [2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride, Catapres®] in cholinergic mechanisms

1969 • 49 citations

Evidence for a central hypotensive mechanism of 2-(2,6-dichlorophenylamino)-2-imidazoline (catapresan, ST-155)

1968 • 49 citations

Studies on the mode of action of alpha-methyldopa.

1969 • 47 citations

Actions of clonidine and 2-(2-methyl-6-ethyl-cyclohexylamino)-2-oxazoline on postganglionic autonomic nerves.

1972 • 46 citations

Clonidine-induced cardiovascular effects after stereotaxic application in the hypothalamus of rats

1972 • 45 citations

GUANETHIDINE AND METHYLDOPA: A HAeMODYNAMIC STUDY

1964 • 45 citations

Modulating effect of central adrenergic neurones on a vagally mediated cardioinhibitory reflex

1973 • 44 citations

A centrally mediated peripheral hypotensive effect of alpha-methyldopa.

1970 • 44 citations

Effects of pentobarbitone and decerebration on the clonidine-induced circulatory changes

1975 • 43 citations

Pharmacology of BS 100-141, a centrally acting antihypertensive drug.

1975 • 40 citations

Effects of centrally applied drugs on pressor responses to hypothalamic stimulation

1974 • 40 citations

Effect of a new hypotensive drug, ST155, on the systemic circulation

1966 • 40 citations

Central and peripheral alpha adrenergic activity of imidazoline derivatives

1974 • 39 citations

Localization in the CNS of adrenoceptors which facilitate a cardioinhibitory reflex

1975 • 39 citations

Effects of sympathetic blocking substances on the diving reflex of ducks

1969 • 39 citations

Clonidine and related analogues. Quantitative correlations

1976 • 39 citations

Cardiac slowing effects of clonidine (ST-155) in dogs.

1970 • 38 citations

General pharmacologic actions of the antihypertensive agent 2,6-dichlorobenzylidene aminoguanidine acetate (WY-8678).

1970 • 37 citations

Noradrenaline synthesis and utilization: Control by nerve impulse flow under normal conditions and after treatment with alpha-adrenoreceptor blocking agents

1976 • 37 citations

Contribution of the central nervous system to the action of several antihypertensive agents (methyldopa, hydralazine and guanethidine).

1972 • 37 citations

Amidines. 2. New class of antihypertensive agents. 1,2,3,5-Tetrahydroimidazo[2,1-b]quinazolines

1972 • 36 citations

Mechanism by Which Serotonin, Norepinephrine and Reserpine Cause Central Vasomotor Inhibition

1960 • 35 citations

Comparison of haemodynamic effects of α-sympathomimetic drugs

1971 • 35 citations

Action of clonidine on baroreceptor reflexes in conscious dogs

1974 • 35 citations

Desmethylimipramine and the hypotensive action of clonidine in the rabbit

1973 • 33 citations

Sites of central nervous action of clonidine of reflex autonomic function in the unanaesthetized rabbit

1971 • 33 citations

The central action of clonidine and its antagonism

1972 • 33 citations

Central effects of sympathomimetic amines on the blood pressure

1971 • 32 citations

Interaction between centrally acting hypotensive drugs and tricyclic antidepressants.

1975 • 32 citations

[On the mechanism of action of a new antihypertensive substance with imidazoline structure].

1967 • 32 citations

Heat capacities and thermodynamic properties of Cr3Te4 and Ni3Te4 from 298 to 950 K. Structural order-disorder transitions

1973 • 32 citations

Studies of the new hypotensive drug ST 155

1968 • 30 citations

Catecholamine release and receptors in brain slices

1973 • 30 citations

An investigation into the bradycardic effects of ST 155 [2-(2,6-dichlorophenylamino)-2-imidazoline HCl] in the anesthetized dog.

1969 • 30 citations

Possible mechanism of the hypotensive action of 2,6-dichlorobenzylidene aminoguanidine: Evidence for central noradrenaline receptor stimulation

1973 • 30 citations

Clonidine Enhances the Secretion of Sympathetic Neurotransmitter from Isolated Guinea‐pig Tissues

1975 • 28 citations

Pharmacodynamics and clinical use of guanethidine, bretylium and methyldopa

1962 • 28 citations

?-Sympathicomimetische Eigenschaften als Ursache der blutdrucksteigernden und blutdrucksenkenden Wirkung von BAY 1470 (2-(2,6-Xylidino)-5,6-dihydro-4H-1,3-thiazinhydrochlorid)

1971 • 28 citations

Further studies on the mechanism of the central hypotensive effect of L-dopa, DL-m-tyrosine and L-α-methyldopa

1971 • 27 citations

Enhancement by Methyldopa of Tyramine Sensitivity in Man

1963 • 26 citations

BLOCKADE OF THE CENTRAL HYPOTENSIVE EFFECT OF CLONIDINE BY ?-ADRENORECEPTOR ANTAGONISTS IN RATS, RABBITS AND DOGS

1974 • 26 citations

Maintenance of tonic vasomotor activity by alpha and beta adrenergic mechanisms in medullary cardiovascular centers.

1974 • 26 citations

The central hypotensive action of amphetamine, ephedrine, phentermine, chlorphentermine and fenfluramine

1972 • 25 citations

CENTRAL VASOMOTOR EFFECTS OF α-METHYL DOPA

1966 • 25 citations

Blood pressure and noradrenaline levels after treatment with α-methyldopa, α-methyldopamine and α-methyl-m-tyrosine

1967 • 22 citations

Further observations on the cardiovascular effects of ST 155 (Catapres).

1969 • 22 citations

Abolition of the renin-releasing action of frusemide by acute renal denervation in dogs

1975 • 22 citations

The centrally induced fall in blood pressure after the infusion of amphetamine and related drugs into the vertebral artery of the cat

1971 • 21 citations

�ber den nachweis und die bedeutung von ?-methylnoradrenalin im harn von hypertonikern bei verabreichung von ?-methyldopa

1968 • 21 citations

Über die zentrale Blutdruckwirkung des Adrenalins

1933 • 21 citations

A technique for recording sympathetic nerve activity in unanaesthetized dogs

1974 • 21 citations

CATECHOLAMINE RELEASE AND RECEPTORS IN BRAIN SLICES

1973 • 21 citations

Strukturuntersuchungen an 2‐(Arylimino)imidazolidinen und 2‐(Arylamino)imidazolinen mit Hilfe der Protonen‐ und Kohlenstoff‐13‐Resonanz

1974 • 20 citations

Effect of clonidine on the synthesis of cerebral dopamine

1975 • 20 citations

STUDIES ON THE HYPOTENSIVE ACTION OF α‐METHYLDOPAMINE

1975 • 20 citations

The effect of clonidine on human isolated smooth muscle

1972 • 19 citations

The Pharmacologic Effects of ST-155 (Catapres) and Related Imidazolines in the Rat

1969 • 18 citations

EFFECT OF CLONIDINE ON THE EXCITABILITY OF VASOMOTOR LOCI IN THE CAT

1975 • 17 citations

Decrease in the sympatho-inhibitory action of clonidine after destruction of the sympatho-inhibitory area

1973 • 17 citations

An effect of ST 155 (clonidine), 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride, catapres® on relationship between blood pressure and heart rate in dogs

1970 • 16 citations

Die Ausbreitung intrazisternal injizierter Stoffe im Liquorraum

1933 • 16 citations

The Central Hypotensive Action of Clonidine and BAY 1470 in Cats and Rats

1974 • 16 citations

Effects of clonidine on baroreceptor function in anesthetized dogs

1975 • 15 citations

Central symphato-inhibitory effects of intracisternal and intravenous administrations of noradrenaline in high doses

1974 • 15 citations

Analysis of the action of m-tyrosine on blood pressure in the conscious rat: evidence for a central hypotensive effect

1971 • 15 citations

The effects of various anti-hypertensive drugs on the reflex responses to vasoactive substances

1970 • 15 citations

Differential effect of baroreceptor reflexes and clonidine on frequency components of sympathetic discharge

1976 • 13 citations

Clonidine base: evidence for conjugation of both ring systems.

1975 • 13 citations

A possible dual role of noradrenaline in cardiovascular responses mediated by the central nervous system

1968 • 12 citations

The effects of 2-(2,6-dichlorphenylamine)-2-imidazoline hydrochloride (Catapres) upon the systemic and coronary haemodynamics and metabolism of intact dogs.

1969 • 12 citations

Role of forebrain in clonidine-induced suppression of cardiovascular responses

1973 • 12 citations

Tiamenidine (Hoe 440), a new antihypertensive substance.

1974 • 11 citations

Synthesen in der 2‐Amino‐imidazolin‐Reihe

1971 • 11 citations

Centrally Induced Hypotension by 2-(2,6-Dichlorophenyl)-5,6-Dihydroimidazo (2, l-b)-Thiazole Fumarate (Compound 44-549)

1975 • 10 citations

Untersuchungen der Zentralnerv�sen sympathicusd�mpfenden Wirkungen von ?-Methyl-dopa

1971 • 10 citations

Mechanism of action of ST 155 on the blood-pressure in rats.

1967 • 10 citations

Reduction of the Hypotensive Effect of Clonidine and α-Methyldopa by Various Psychotropic Drugs

1976 • 10 citations

The effect of St 155 on the active reflex vasodilatation induced by adrenaline, noradrenaline and veratrine

1969 • 10 citations

Valsalva Vasoconstrictor Reflex in Human Hypertension and after β-Adrenoreceptor Blockade in Conscious Rabbits

1976 • 9 citations

THE MODE OF HYPOTENSIVE ACTIONS OF 2-(2,6-DIGHLOROPHENYL-L-AMINO)-IMIDAZOLINE IN THE RABBIT

1969 • 7 citations

Influence of desmethylimipramine on the hypotensive effect of clonidine.

1974 • 7 citations

Circulatory Effects of Clonidine after Pre‐hypothalamic Section in the Rat

1976 • 7 citations

Zur peripheren sympathikushemmenden Wirkung des Clonidins

1971 • 6 citations

ChemInform Abstract: CLONIDINE AND RELATED ANALOGUES. QUANTITATIVE CORRELATIONS

1976 • 5 citations

Comparison between the effects of ST 600 and catapres.

1975 • 3 citations

[A new antihypertensive imidazoline derivative (St 600, Fluoronidine): I. Haemodynamic investigations at rest and during exercise (author's transl)].

1976 • 2 citations

Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. II. Action on cardiac contraction, circulatory parameters, autonomic receptors and diuresis.

1975 • 2 citations

Studies on orthostatic cardiovascular responses in anaesthetized cats.

1975 • 2 citations

Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (Tolonidine), a new antihypertensive agent. I. Action on blood pressure and heart rate.

1975 • 1 citations

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