Serotonin (5-HT) in brains of adult patients with Down Syndrome

The Metabolic and Molecular Bases of Inherited Disease

1995 • 12,086 citations

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

1991 • 4,669 citations

Structure and function of the brain serotonin system

1992 • 2,507 citations

Basic Neurochemistry: Molecular, Cellular, and Medical Aspects

1989 • 1,360 citations

The spectrum of behaviors influenced by serotonin

1998 • 1,126 citations

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome

1985 • 1,125 citations

Basic Neurochemistry: Molecular, Cellular, and Medical Aspects

1989 • 837 citations

Neurotransmitters as growth regulatory signals: role of receptors and second messengers

1993 • 806 citations

The NINCDS‐ADRDA Work Group criteria for the clinical diagnosis of probable Alzheimer's disease

1988 • 611 citations

Neurochemical Correlates of Dementia Severity in Alzheimer's Disease: Relative Importance of the Cholinergic Deficits

1995 • 572 citations

Genetically driven variation in serotonin uptake: is there a link to affective spectrum, neurodevelopmental, and neurodegenerative disorders?

1998 • 344 citations

Biochemical changes in Dementia disorders of Alzheimer type (AD/SDAT)

1983 • 296 citations

Catecholamines and cholinergic enzymes in pre-senile and senile Alzheimer-type dementia and down's syndrome

1983 • 250 citations

Growth and development of the brain in Down syndrome.

1991 • 209 citations

Possible neurotransmitter basis of behavioral changes in alzheimer's disease

1988 • 190 citations

Neuropsychological evaluation of adults with Down's syndrome: patterns of selective impairment in non‐demented old adults

1989 • 184 citations

Awakening the sleeping giant: anatomy and plasticity of the brain serotonergic system.

1991 • 177 citations

Presynaptic Serotonergic Markers in Community‐Acquired Cases of Alzheimer's Disease: Correlations with Depression and Neuroleptic Medication

1996 • 134 citations

Imaging of the serotonergic system: interactions of neuroanatomical and functional abnormalities of depression

1998 • 133 citations

Alzheimer-like neurotransmitter deficits in adult Down's syndrome brain tissue.

1987 • 106 citations

Neurotransmitter deficits in Alzheimer's disease and in other dementing disorders.

1986 • 105 citations

Functional Effects of Striatal Dysfunction in Parkinson Disease

1997 • 101 citations

Allelic functional variation of serotonin transporter expression is a susceptibility factor for late onset Alzheimerʼs disease

1997 • 100 citations

PATHOLOGICAL EVIDENCE FOR NEUROTRANSMITTER DEFICITS IN DOWN'S SYNDROME OF MIDDLE AGE

1985 • 98 citations

Monoamine oxidase inhibitors increase preferentially extracellular 5-hydroxytryptamine in the midbrain raphe nuclei. A brain microdialysis study in the awake rat

1993 • 98 citations

REVERSAL OF HYPOTONIA IN INFANTS WITH DOWN'S SYNDROME BY ADMINISTRATION OF 5-HYDROXYTRYPTOPHAN

1967 • 95 citations

BLOOD-SEROTONIN DEFICIENCY IN DOWN'S SYNDROME

1965 • 89 citations

Down syndrome and Alzheimer disease.

1992 • 89 citations

Infantile spasms associated with 5‐hydroxytryptophan administration in patients with Down's syndrome

1971 • 86 citations

Major Depression in Down's Syndrome

1989 • 84 citations

Excitatory amino acids and monoamines in parahippocampal gyrus and frontal cortical pole of adults with down syndrome

1997 • 76 citations

Release of Serotonin in the Rat Locus Coeruleus: Effects of Cardiovascular, Stressful and Noxious Stimuli

1997 • 53 citations

Regional brain 5-hydroxytryptamine levels are reduced in senile Down's syndrome as in Alzheimer's disease

1986 • 50 citations

Some morphometric observations on the brains of patients with Down's syndrome: their relationship to age and dementia

1990 • 49 citations

Dietary increase in serotonin reduces self‐injurious behaviour in a Down's syndrome adult

1990 • 34 citations

Serotonergic treatment for aggression in a Down's syndrome adult showing signs of Alzheimer's disease

1991 • 33 citations

Treatment of Functional Decline in Adults with down Syndrome Using Selective Serotonin-Reuptake Inhibitor Drugs

1997 • 33 citations

Age Stability of Human Brain 5-HT Terminals Studied with [<sup>3</sup>H]Paroxetine Binding

1992 • 30 citations

The effect of age on the monoamines of the hypothalamus

1995 • 19 citations

The use of 5-HTP in the treatment of Down's syndrome.

1974 • 16 citations

The Use of 5-HTP in the Treatment of Down's Syndrome

1974 • 14 citations

Deleted Work

1955 • 0 citations