The Nucleases of Escherichia coli

Genetic regulatory mechanisms in the synthesis of proteins

1961 • 6,378 citations

The nucleic acids

1955 • 2,045 citations

The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides

1961 • 1,559 citations

A fine-structure genetic and chemical study of the enzyme alkaline phosphatase of E. Coli I. Purification and characterization of alkaline phosphatase

1960 • 1,407 citations

Personal communication

2017 • 1,128 citations

MULTIPLE FORMS OF ENZYMES: TISSUE, ONTOGENETIC, AND SPECIES SPECIFIC PATTERNS

1959 • 1,097 citations

The Chemical Basis of Heredity

1957 • 1,044 citations

Influence of inorganic phosphate in the formation of phosphatases by Escherichia coli

1960 • 814 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1961 • 758 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1958 • 690 citations

DEOXYRIBONUCLEIC ACID-DIRECTED SYNTHESIS OF RIBONUCLEIC ACID BY AN ENZYME FROM ESCHERICHIA COLI

1962 • 628 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1962 • 621 citations

Biological Structure and Function

1960 • 556 citations

Host specificity of DNA produced by Escherichia coli

1962 • 453 citations

PROGRESS IN NUCLEIC ACID RESEARCH

1966 • 408 citations

The Deoxyribonucleases of Escherichia coli

1960 • 396 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1960 • 378 citations

Informational Macromolecules

1962 • 368 citations

CHARACTERISTICS AND STABILIZATION OF DNAASE-SENSITIVE PROTEIN SYNTHESIS IN E. COLI EXTRACTS

1961 • 343 citations

The Chemical Basis of Heredity

1961 • 286 citations

ENZYMATIC INCORPORATION OF RIBONUCLEOSIDE TRIPHOSPHATES INTO THE INTERPOLYNUCLEOTIDE LINKAGES OF RIBONUCLEIC ACID

1960 • 279 citations

The formation of hybrid DNA molecules and their use in studies of DNA homologies

1961 • 276 citations

A Study of the Substrate Specificity and Other Properties of the Alkaline Phosphatase of Escherichia coli

1962 • 272 citations

ENZYMATIC SYNTHESIS AND BREAKDOWN OF DESOXYRIBOSE PHOSPHATE

1952 • 255 citations

CHROMOSOME BREAKAGE ACCOMPANYING GENETIC RECOMBINATION IN BACTERIOPHAGE

1961 • 251 citations

The Deoxyribonucleases of Escherichia coli

1962 • 242 citations

Purification and Mechanism of Action of Ribonuclease from Escherichia coli Ribosomes

1961 • 239 citations

Alkaline Phosphatase of Escherichia coli: A Zinc Metalloenzyme^*

1962 • 230 citations

THE ENZYMATIC SYNTHESIS OF PURINE RIBOSIDES

1947 • 228 citations

A DEOXYRIBONUCLEASE FROM CALF SPLEEN

1957 • 224 citations

Host specificity of DNA produced by Escherichia coli

1962 • 223 citations

The localization of alkaline phosphatase in E., coli K12

1961 • 217 citations

Polyamines and Ribosome Structure

1960 • 217 citations

A NEW TWO STRANDED HELICAL STRUCTURE: POLYADENYLIC ACID AND POLYURIDYLIC ACID

1956 • 211 citations

The enzymically catalysed transfer of the deoxyribosyl group from one purine or pyrimidine to another

1952 • 209 citations

SYNTHETIC POLYNUCLEOTIDES AND THE AMINO ACID CODE

1961 • 200 citations

ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. INFLUENCE OF BACTERIOPHAGE T2 ON THE SYNTHETIC PATHWAY IN HOST CELLS

1959 • 200 citations

Determination of the Helical Configuration of Ribonucleic Acid Molecules by X-Ray Diffraction Study of Crystalline Amino-Acid–transfer Ribonucleic Acid

1962 • 199 citations

A Possible Negative Feedback Phenomenon controlling Formation of Alkaline Phosphomonoesterase in Escherichia coli

1959 • 185 citations

CRYSTALLINE DESOXYRIBONUCLEASE

1950 • 185 citations

Studies on Polynucleotides. VIII.¹ Experiments on the Polymerization of Mononucleotides. Improved Preparation and Separation of Linear Thymidine Polynucleotides. Synthesis of Corresponding Members Terminated in Deoxycytidine Residues²

1961 • 184 citations

A Deoxyribonuclease of Micrococcus pyogenes¹

1956 • 181 citations

Latent enzymic activity of a ribonucleoprotein isolated from Escherichia coli

1959 • 178 citations

REVERSIBLE SYNTHESIS OF POLYRIBONUCLEOTIDES WITH AN ENZYME FROM ESCHERICHIA COLI

1957 • 174 citations

X-ray studies of two synthetic DNA copolymers

1963 • 167 citations

Studies on Polynucleotides

1959 • 165 citations

Bacteriocidal action of mitomycin C

1961 • 152 citations

The Purification and Properties of Micrococcal Nuclease

1961 • 142 citations

Formation of Deoxycytidine Phosphates from Cytidine Phosphates in Extracts from Escherichia coli

1961 • 142 citations

Glucosylation of Deoxyribonucleic Acid by Enzymes from Bacteriophage-infected Escherichia coli

1961 • 141 citations

Virus-induced Acquisition of Metabolic Function

1959 • 141 citations

Electron microscopical studies of phage multiplication

1959 • 136 citations

The enzymic incorporation of ribonucleotides into polyribonucleotides and the effect of DNA

1960 • 136 citations

THE CHEMICAL NATURE OF THE RNA-AMINO ACID COMPOUND FORMED BY AMINO ACID-ACTIVATING ENZYMES

1959 • 133 citations

Enzymatic Synthesis of Deoxyribonucleotides

1962 • 132 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1962 • 131 citations

Vegetative Bacteriophage and the Maturation of the Virus Particles

1962 • 129 citations

Nucleotide exchange reactions catalysed by ribonuclease and spleen phosphodiesterase. 2. Synthesis of polynucleotides

1955 • 124 citations

Molecular and Biological Characterization of Messenger RNA

1961 • 123 citations

Studies on ribonuclease in tobacco leaves I. Purification and properties

1957 • 123 citations

CHROMATIN STAINING OF BACTERIA DURING BACTERIOPHAGE INFECTION

1950 • 121 citations

EXCHANGE OF DNA IN THE RECOMBINATION OF BACTERIOPHAGE λ

1961 • 121 citations

THE EFFECT OF HYDRODYNAMIC SHEAR ON THE DEOXYRIBONUCLEIC ACID FROM T ₂ AND T ₄ BACTERIOPHAGES

1959 • 119 citations

Incorporation of the adenine ribonucleotide into RNA by cell fractions from E. coli B

1960 • 117 citations

Enzymatic synthesis of DNA.

1963 • 113 citations

Latent ribonuclease activity in a ribonucleoprotein

1958 • 112 citations

The structure of the DNA of bacteriophage φX174

1962 • 111 citations

ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. IV. LINKAGE OF SINGLE DEOXYNUCLEOTIDES TO THE DEOXYNUCLEOSIDE ENDS OF DEOXYRIBONUCLEIC ACID

1958 • 109 citations

THE EFFECT OF ENZYMATICALLY SYNTHESIZED RIBONUCLEIC ACID ON AMINO ACID INCORPORATION BY A SOLUBLE PROTEIN-RIBOSOME SYSTEM FROM ESCHERICHIA COLI

1962 • 108 citations

Purification and properties of a pyrimidine deoxyriboside phosphorylase from Escherichia coli

1958 • 106 citations

Breakdown of Messenger Ribonucleic Acid by a Potassium-activated Phosphodiesterase from Escherichia coli

1963 • 105 citations

ORIGIN AND FATE OF BACTERIOPHAGE MATERIAL

1953 • 104 citations

Enzymatic synthes is of RNA

1960 • 104 citations

Glucosylation of Deoxyribonucleic Acid

1962 • 103 citations

MUTANTS OF ESCHERICHIA COLI CONSTITUTIVE FOR ALKALINE PHOSPHATASE

1961 • 101 citations

A NEW MODE OF ENZYMATIC PHOSPHATE TRANSFER

1948 • 100 citations

Virus-induced Acquisition of Metabolic Function

1959 • 99 citations

Tissue and Intracellular Distribution of Two Phosphodiesterases

1961 • 98 citations

PHOSPHOROLYSIS AND HYDROLYSIS OF PURINE RIBOSIDES BY ENZYMES FROM YEAST

1952 • 98 citations

A DEOXYRIBONUCLEASE FROM CALF SPLEEN

1957 • 96 citations

ENZYMATIC DEAMINATION OF CYTOSINE NUCLEOSIDES

1950 • 91 citations

Deoxycytidine Di- and Triphosphate Cleavage by an Enzyme Formed in Bacteriophage-infected Escherichia coli

1961 • 88 citations

Enzymatic Cleavage of Deoxyguanosine Triphosphate to Deoxyguanosine and Tripolyphosphate

1958 • 87 citations

The Selective Degradation of Phage-induced Ribonucleic Acid by Polynucleotide Phosphorylase

1963 • 85 citations

The structure of the DNA of bacteriophage φX174

1963 • 85 citations

Synthesis of Pyrimidine Deoxyribonucleoside Diphosphates with Enzymes from Escherichia coli

1961 • 83 citations

Synthesis of deoxycytidine-5′-phosphate deaminase in Escherichia coli infected by T2 bacteriophage

1960 • 82 citations

DEOXYRIBONUCLEIC ACID-DEPENDENT INCORPORATION OF NUCLEOTIDES FROM NUCLEOSIDE TRIPHOSPHATES INTO RIBONUCLEIC ACID

1961 • 80 citations

THE METABOLISM OF DESOXYRIBOSE NUCLEOSIDES IN ESCHERICHIA COLI

1951 • 80 citations

Bacterial uracil riboside phosphorylase

1952 • 79 citations

The Deoxyribonucleases of Escherichia coli

1962 • 78 citations

DEOXYURIDYLATE KINASE ACTIVITY AND DEOXYURIDINETRIPHOSPHATASE IN ESCHERICHIA COLI

1962 • 76 citations

Nutrition of Bacteria and Fungi

1957 • 75 citations

Intracellular Distribution of Acid and Alkaline Ribonuclease in Normal Rat Liver

1954 • 74 citations

Partial Purification of a Non-phosphorylytic Uridine Nucleosidase from Yeast

1951 • 74 citations

The partial purification of leaf ribonuclease

1955 • 73 citations

THE DIFFERENTIATION OF THREE DISTINCT DESOXYRIBONUCLEASES OF GROUP A STREPTOCOCCI

1958 • 72 citations

Enzymatic synthesis of DNA

1963 • 72 citations

RIBONUCLEASE

1954 • 72 citations

The Crystal and Molecular Structure of N-Methyluracil

1962 • 69 citations

Purification and Properties of Trans-N-Deoxyribosylase

1958 • 68 citations

The reaction of formaldehyde with denatured DNA: Spectrophotometric, immunologic, and enzymic studies

1962 • 68 citations

On the distribution and biological significance of the nucleoside phosphotransferases

1955 • 67 citations

STUDIES ON CONTROLLING MECHANISMS IN THE METABOLISM OF VIRUS-INFECTED BACTERIA

1953 • 66 citations

PHOSPHOROLYSIS OF OLIGORIBONUCLEOTIDES BY POLYNUCLEOTIDE PHOSPHORYLASE

1958 • 65 citations

Untersuchungen zur Biosynthese der Proteine, III. Beitrag zur Kenntnis der Zusammensetzung und Struktur der Ribosomen

1959 • 62 citations

Formation of deoxycytidine 5′-phosphate from cytidine 5′-phosphate with enzymes from Escherichia coli

1960 • 60 citations

The autodegradation of ribonucleoprotein in Escherichia coli

1961 • 59 citations

HYDROXYMETHYLDEOXYCYTIDYLATE KINASE FORMATION AFTER BACTERIOPHAGE INFECTION OF ESCHERICHIA COLI

1959 • 59 citations

THE METABOLISM OF HYPOXANTHINE DESOXYRIBOSIDE IN ANIMAL TISSUES

1951 • 59 citations

Phosphorolyse et configuration macromoléculaire des polyribonucléotides biosynthétiques et des acides ribonucléiques

1959 • 59 citations

Nucleic acid metabolism in Escherichia coli infected with phage T5

1959 • 58 citations

Acid phosphatases of Escherichia coli

1960 • 58 citations

STUDIES ON THE BIOSYNTHESIS OF BACTERIAL AND VIRAL PYRIMIDINES

1957 • 58 citations

Deoxyribonucleotide Kinases in Normal and Virus-infected Escherichia coli

1959 • 58 citations

Nucleotide exchange reactions catalysed by ribonuclease and spleen phosphodiesterase. 1. Synthesis and interconversion of simple esters of ribomononucleotides

1955 • 57 citations

STUDIES ON ISOMERIC DINUCLEOTIDES DERIVED FROM DEOXYRIBONUCLEIC ACID

1957 • 55 citations

Studies on a Nuclease from Azotobacter agilis

1960 • 55 citations

Studies on tobacco leaf ribonuclease

1958 • 53 citations

The Properties of Adenosine Deaminase and Adenosine Nucleoside Phosphorylase in Extracts of Escherichia coli

1959 • 53 citations

Enzymic synthesis of polynucleotides. III. Phosphorolysis of natural and synthetic ribopolynucleotides

1957 • 52 citations

OPTICAL CHANGES OCCURRING DURING THE ACTION OF PHOSPHODIESTERASE ON OLIGONUCLEOTIDES DERIVED FROM DEOXYRIBONUCLEIC ACID

1956 • 52 citations

Formation of hybrid molecules from two alternating DNA copolymers

1962 • 51 citations

On the action mechanism of mitomycin C

1961 • 51 citations

The Enzymology of Virus-infected Bacteria

1961 • 51 citations

Studies on the Mechanism of Action of Polynucleotide Phosphorylase

1960 • 51 citations

THE MECHANISM OF ACTION OF LACTOBACILLUS PENTOSUS NUCLEOSIDASE

1952 • 50 citations

Deoxycytidine Triphosphatase, an Enzyme Induced by Bacteriophage Infection

1960 • 49 citations

The mode of action of ryegrass ribonuclease

1959 • 49 citations

RIBONUCLEASE

1957 • 49 citations

The Conversion of a Phage-induced Ribonucleic Acid to Deoxyribonucleotides in Vitro

1961 • 45 citations

ENZYMES HYDROLYZING DNA*

1959 • 44 citations

Studies on the deoxyribonucleases of bacteriophage-infected Escherichia coli

1962 • 41 citations

Polynucleotide phosphorylase in ribosomes from Escherichia coli

1961 • 40 citations

The biologic activity of enzymically-altered E., coli transfer RNA

1962 • 40 citations

Bacteriocidal action of mitomycin C

1960 • 40 citations

Glucosylation of Deoxyribonucleic Acid

1962 • 39 citations

The metabolism of adenine compounds by Bact. coli

1938 • 39 citations

Biochemical differences in ribonucleoproteins

1959 • 36 citations

The decomposition of adenine compounds by bacteria

1936 • 33 citations

KETONE BODY FORMATION FROM TYROSINE

1948 • 33 citations

Ribonucleases of rat liver

1958 • 32 citations

Studies on the role of deoxyribonuclease in T2 bacteriophage development

1956 • 31 citations

THE EFFECT OF END GROUPS AND THE INITIAL SITE OF ATTACK ON POLYNUCLEOTIDES BY POLYNUCLEOTIDE PHOSPHORYLASE AND CERTAIN PHOSPHODIESTERASES

1959 • 31 citations

An ultracentrifugal study of the efficiency of some macromolecular inhibitors of ribonuclease

1962 • 30 citations

SOME ENZYMES OF NUCLEOSIDE METABOLISM OF ESCHERICHIA COLI

1956 • 29 citations

ENZYME ACTIVITY AND BACTERIOPHAGE INFECTION

1952 • 28 citations

Metabolism of Adenosine and Deoxyadenosine by Growing Cultures of Escherichia coli

1960 • 28 citations

The action of phosphoglucomutase preparations on ribose 1-phosphate

1952 • 28 citations

STUDIES OF SPECIFICITY OF DEOXYRIBONUCLEASE II FROM THYMUS

1957 • 27 citations

BREAKDOWN OF MESSENGER RNA DURING IN VITRO AMINO ACID INCORPORATION INTO PROTEINS

1962 • 27 citations

The increase in desoxyribonuclease of virus-infected E. coli

1952 • 26 citations

PURIFICATION AND CHARACTERIZATION OF RIBONUCLEASE OF CALF SPLEEN

1959 • 26 citations

INTRACELLULAR LOCALIZATION AND CHROMATOGRAPHY OF MOUSE PANCREAS RIBONUCLEASES*

1959 • 25 citations

The Effect of Lysogenic Induction on the Deoxyribonucleases of Escherichia coli K12λ

1962 • 22 citations

A change in the properties of deoxyguanylate kinase of E. coli caused by viral infection

1959 • 20 citations

THE PURINE AND PYRIMIDINE METABOLISM OF NORMAL AND PHAGE-INFECTED ESCHERICHIA COLI

1953 • 19 citations

Partial purification of DNase II from thymus

1954 • 17 citations

THE MECHANISM OF ACTION OF POLYNUCLEOTIDE PHOSPHORYLASE

1959 • 17 citations

The Enzymology of Virus-infected Bacteria

1961 • 13 citations

Stepwise synthesis of deoxyribo-oligonucleotides

1963 • 13 citations

Acid Phosphatases in Escherichia coli.

1961 • 12 citations

Biochemical Studies of Lysogeny

1960 • 11 citations

Deoxyribonuclease activity in Escherichia coli K12 (λ) after bacteriophage induction with ultraviolet irradiation

1957 • 10 citations

The enzymology of virus-infected bacteria

1961 • 8 citations

The purity of thyroglobulin isolated from normal and carcinomatous thyroid tissue on one patient by fractional salting-out with ammonium sulphate

1958 • 8 citations