COMPARATIVE STUDY OF THE POTENCY AND SELECTIVITY OF ANTI-HERPES COMPOUNDS

Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanine

1977 • 1,565 citations

9-(2-Hydroxyethoxymethyl)guanine activity against viruses of the herpes group

1978 • 1,136 citations

Adenine Arabinoside Therapy of Biopsy-Proved Herpes Simplex Encephalitis

1977 • 691 citations

Adenine Arabinoside Therapy of Herpes Zoster in the Immunosuppressed

1976 • 293 citations

( S )-9-(2,3-Dihydroxypropyl)adenine: An Aliphatic Nucleoside Analog with Broad-Spectrum Antiviral Activity

1978 • 237 citations

Mechanism of phosphonoacetate inhibition of herpesvirus-induced DNA polymerase

1976 • 207 citations

Inhibition of DNA Polymerase from Herpes Simplex Virus-Infected Wi-38 Cells by Phosphonoacetic Acid

1975 • 174 citations

Adverse Effect of Cytosine Arabinoside on Disseminated Zoster in a Controlled Trial

1973 • 173 citations

Adenine Arabinoside: An Antiviral Agent

1975 • 166 citations

Inhibition of Herpes Simplex Virus Replication by Phosphonoacetic Acid

1974 • 148 citations

Selective Inhibitors of Viral Functions.

1974 • 141 citations

Mode of inhibition of Herpes simplex virus DNA polymerase by phosphonoacetate

1975 • 138 citations

INHIBITION OF HERPESVIRUS DNA SYNTHESIS BY 9‐β‐D‐ARABINOFURANOSYLADENINE IN CELLULAR AND CELL‐FREE SYSTEMS *

1977 • 114 citations

Suppression of Herpes Simplex Virus Infection by Phosphonoacetic Acid

1973 • 113 citations

Antiviral Activity of Arabinosylthymine in Herpesviral Replication: Mechanism of Action In Vivo and In Vitro

1977 • 101 citations

Antiviral Action and Cellular Toxicity of Four Thymidine Analogues: 5-Ethyl-, 5-Vinyl-, 5-Propyl-, and 5-Allyl-2′-Deoxyuridine

1976 • 100 citations

Inhibition of herpes simplex virus replication by araT

1975 • 95 citations

Nucleoside analogs with antiviral activity

1976 • 91 citations

Synthesis and antiviral activity of 5- and 5'-substituted thymidine analogs

1976 • 77 citations

RELATIVE POTENCIES OF ANTI‐HERPES COMPOUNDS

1977 • 76 citations

Antiviral activity of 5-ethyl pyrimidine deoxynucleosides

1975 • 75 citations

Specific herpes simplex virus-induced incorporation of 5-iodo-5'-amino-2',5'-dideoxyuridine into deoxyribonucleic acid.

1976 • 74 citations

Suppression of Herpes Simplex Virus Infection by Phosphonoacetic Acid

1973 • 72 citations

Selective inhibition of herpes simplex virus by 5-amino-2,5-dideoxy-5-iodouridine

1975 • 70 citations

Differential effect of arabinofuranosylthymine of the replication of human herpesviruses

1977 • 66 citations

Enzymatic basis for the selective inhibition of varicella-zoster virus by 5-halogenated analogues of deoxycytidine

1976 • 66 citations

Phosphorylation of 5-Bromodeoxycytidine in Cells Infected with Herpes Simplex Virus

1973 • 55 citations

THE SELECTIVE INHIBITION OF VIRAL DNA SYNTHESIS BY CHEMOTHERAPEUTIC AGENTS: AN INDICATOR OF CLINICAL USEFULNESS? *

1977 • 54 citations

5-Nitro-2'-deoxyuridine and 5-nitro-2'-deoxyuridine 5'-monophosphate: antiviral activity and inhibition of thymidylate synthetase in vivo.

1978 • 54 citations

Comparison of the Antiviral Effects of 5-Methoxymethyl-deoxyuridine with 5-Iododeoxyuridine, Cytosine Arabinoside, and Adenine Arabinoside

1975 • 45 citations

Selective inhibition of the replication of herpes simplex virus by 5-halogenated analogues of deoxycytidine.

1975 • 41 citations

5-Propyl-2'-deoxyuridine: a specific anti-herpes agent

1978 • 36 citations

5-O-Alkylated derivatives of 5-hydroxy-2'-deoxyuridine as potential antiviral agents. Anti-herpes activity of 5-propynyloxy-2'-deoxyuridine

1978 • 34 citations

The synthesis and properties of some antiviral nucleosides

1978 • 31 citations

The synthesis of nucleosides derived from 5-ethynyluracil and 5-ethynylcytosine

1978 • 30 citations

Anti-herpes activity of deoxythymidine analogues: specific dependence on virus-induced deoxythymidine kinase.

1977 • 27 citations

Assessment of Cytosine Arabinoside as an Antiviral Agent in Humans

1974 • 24 citations

Variables Influencing the In Vitro Susceptibilities of Herpes Simplex Viruses to Antiviral Drugs

1974 • 21 citations

Induction of deoxycytidine deaminase activity in mammalian cell lines by infection with herpes simplex virus type 1.

1977 • 20 citations

Therapy of Experimental Herpes Simplex Keratitis in Rabbits with 5-lodo-5'-Amino-2',5'-Dideoxyuridine

1977 • 17 citations

Effect of 1-beta-D-arabinofuranosylcytosine on DNA synthesis. II. In rabbit kidney cells infected with herpes viruses.

1968 • 17 citations

RELATIONSHIP OF STRUCTURE AND ANTIVIRAL ACTIVITY OF 9‐β‐D‐ARABINOFURANOSYLADENINE ANALOGS

1977 • 13 citations

ChemInform Abstract: 5‐O‐ALKYLATED DERIVATIVES OF 5‐HYDROXY‐2′‐DEOXYURIDINE AS POTENTIAL ANTIVIRAL AGENTS. ANTI‐HERPES ACTIVITY OF 5‐PROPYNYLOXY‐2′‐DEOXYURIDINE

1978 • 3 citations