Non-heme iron dioxygenases structure and mechanism

Molecular Mechanisms of Oxygen Activation

1974 • 879 citations

Inorganic Biochemistry

1974 • 834 citations

On the Specificity of the Oxygenation of Unsaturated Fatty Acids Catalyzed by Soybean Lipoxidase

1967 • 660 citations

Iron-sulfur proteins,

1973 • 463 citations

Demonstration by EPR spectroscopy of the functional role of iron in soybean lipoxygenase-1

1975 • 300 citations

Mechanism of the Prolyl Hydroxylase Reaction

1977 • 260 citations

Mechanism of the Prolyl Hydroxylase Reaction

1977 • 247 citations

Protocatechuate 3,4-Dioxygenase

1968 • 237 citations

Oxygenation of Unsaturated Fatty Acids by Soybean Lipoxygenase

1972 • 232 citations

Resonance Raman scattering from iron(III)- and copper(II)-transferrin and an iron(III) model compound. Spectroscopic interpretation of the transferrin binding site

1974 • 230 citations

A resonance Raman study of the copper protein, hemocyanin. New evidence for the structure of the oxygen-binding site

1976 • 176 citations

Iron, an Essential Component of Lipoxygenase

1974 • 151 citations

The detection of linoleic acid radicals in the anaerobic reaction of lipoxygenase

1973 • 149 citations

Mössbauer studies of cytochrome P-450_cam

1973 • 127 citations

The influence of oxygen on the fluorescence of lipoxygenase

1973 • 123 citations

Studies on Pyrocatechase

1967 • 121 citations

The Steady-State Kinetics of the Oxygenation of Linoleic Acid Catalysed by Soybean Lipoxygenase

1976 • 114 citations

Mössbauer and EPR spectroscopy on protocatechuate 3,4-dioxygenase from Pseudomonas aeruginosa

1976 • 113 citations

The Formation of threo‐11‐Hydroxy‐trans‐12: 13‐epoxy‐9‐cis‐octadecenoic Acid by Enzymic Isomerisation of 13‐<scp>l</scp>‐Hydroperoxy‐9‐cis,11‐trans‐octadecadienoic Acid by Soybean Lipoxygenase‐1

1976 • 112 citations

Cleavage of carbon-carbon bonds. Copper(II)-induced oxygenolysis of o-benzoquinones, catechols, and phenols. On the question of nonenzymic oxidation of aromatics and activation of molecular oxygen

1978 • 109 citations

Ultraviolet resonance Raman study of oxytyrosinase. Comparison with oxyhemocyanins

1978 • 108 citations

Iron(III)-ethylenediaminetetraacetic acid-peroxide system

1970 • 103 citations

The origin and structures of dimeric fatty acids from the anaerobic reaction between soya-bean lipoxygenase, linoleic acid and its hydroperoxide

1972 • 100 citations

Organic synthesis by metal complexes. XIII. Efficient, nonenzymic oxidation of catechol with molecular oxygen activated by cuprous chloride to cis,cis-muconate as the model reaction for pyrocatechase

1974 • 95 citations

Tertiary structure of myohemerythrin at low resolution.

1975 • 92 citations

Extradiol cleavage of 3-substituted catechols by an intradiol dioxygenase, pyrocatechase, from a Pseudomonad.

1975 • 87 citations

Resonance Raman spectra of iron(III)-, copper(II)-, cobalt(III)-, and manganese(III)-transferrins and of bis(2,4,6-trichlorophenolato)diimidazolecopper(II) monohydrate, a possible model for copper(II) binding to transferrins

1976 • 83 citations

On the interaction of soybean lipoxygenase‐1 and 13‐L‐hydroperoxylinoleic acid, involving yellow and purple coloured enzyme species

1975 • 83 citations

Ferric porphyrin thiolates. Possible relation to cytochrome P-450 enzymes and the structure of (p-nitrobenzenethiolato)iron(III) protoporphyrin IX dimethylester

1975 • 82 citations

Evidence for participation of iron in lipoxygenase reaction from optical and electron spin resonance studies.

1976 • 82 citations

Metal-catalyzed Oxidation of 3,5-di-t-Butyl Pyrocatechol, and Its Significance in the Mechanism of Pyrocatechase Action^*

1964 • 78 citations

Protocatechuate 3,4-Dioxygenase

1972 • 78 citations

Chemistry of superoxide ion. I. Oxidation of 3,5-di-tert-butylcatechol with potassium superoxide

1976 • 74 citations

Resonance Raman studies on pyrocatechase

1979 • 73 citations

Mössbauer effect in rubredoxin. Determination of the hyperfine field of the iron in a simple iron–sulphur protein

1972 • 72 citations

Protocatechuate 3,4-Dioxygenase

1972 • 66 citations

On the Mechanism of Action of Soybean Lipoxygenase-1. A Stopped-Flow Kinetic Study of the Formation and Conversion of Yellow and Purple Enzyme Species

1977 • 62 citations

Catechol 1,2-dioxygenase from Acinetobacter calcoaceticus: purification and properties

1976 • 61 citations

Prolyl hydroxylase half reaction: peptidyl prolyl-independent decarboxylation of alpha-ketoglutarate.

1978 • 60 citations

THE MEASUREMENT OF ZERO FIELD SPLITTING AND THE DETERMINATION OF LIGAND COMPOSITION IN MONONUCLEAR NONHEME IRON PROTEINS *

1973 • 58 citations

Synthetic analogs of active sites of iron-sulfur proteins: bis (o-xylyldithiolato) ferrate (III) monoanion, a structurally unconstrained model for the rubredoxin Fe-S4 unit.

1975 • 56 citations

Protocatechuate 3,4-dioxygenase from Acinetobacter calcoaceticus

1976 • 55 citations

4-Nitrocatechol as a colorimetric probe for non-heme iron dioxygenases.

1975 • 54 citations

A resonance Raman study of substrate and inhibitor binding to protocatechuate-3,4-dioxygenase

1978 • 54 citations

Resonance Raman spectra of protocatechuate 3,4-dioxygenase. Evidence for coordination of tyrosine residue to ferric iron

1978 • 53 citations

Partial reaction of prolyl hydroxylase. (Gly-PRO-Ala)n stimulates alpha-ketoglutarate decarboxylation without prolyl hydroxylation.

1978 • 51 citations

Resonance Raman Studies of the Electronic State of Oxygen in Hemerythrin

1973 • 51 citations

Characteristics of Catechol Oxygenase from Brevibacterium fuscum

1963 • 51 citations

Raman spectral evidence for tyrosine coordination of iron in protocatechuate 3,4-dioxygenase

1978 • 50 citations

Changes in the fluorescence and absorbance of lipoxygenase-1 induced by 13-lS-Hydroperoxylinoleic acid and linoleic acid

1975 • 49 citations

Nonidentical subunits of protocatechuate 3,4-dioxygenase

1976 • 49 citations

Studies on Pyrocatechase

1969 • 47 citations

Organic synthesis by means of metal complexes. XIV. Oxidative cleavage of catechol with labeled oxygen activated by cuprous chloride

1975 • 46 citations

Structure of the iron complex in methemerythrin.

1976 • 44 citations

The electronic state of iron in some natural iron compounds: Determination by Mössbauer and ESR spectroscoopy

2007 • 44 citations

Base-catalyzed oxygenation of tert-butylated phenols. 1. Regioselectivity in the base-catalyzed oxygenation of tert-butylphenols

1978 • 42 citations

Kinetics of the base-catalyzed decomposition of .alpha.-hydroperoxy ketones

1975 • 42 citations

Base-catalyzed oxygenation of tert-butylated phenols. 2. Formation of 3-aryl-2,5-di-tert-butyl-2,4-cyclopentadienones by base-catalyzed oxygenation of 4-aryl-2,6-di-tert-butylphenols: x-ray structure determination of 2,5-di-tert-butyl-3-(4-chlorophenyl)cyclopentadienone

1978 • 39 citations

Reaction of singlet oxygen with .alpha.-ketocarboxylic acids. Oxidative decarboxylation and peroxyacid formation

1976 • 38 citations

α‐Ketoglutarate in biological hydroxylations

1968 • 33 citations

Nonidentical subunits of pyrocatechase from Pseudomonas arvilla C-1

1979 • 31 citations

Oxidative cleavage of phenol to monomethyl muconate by using cuprous chloride

1976 • 30 citations

High-field Mössbauer studies of reduced protocatechuate 3,4-dioxygenase

1978 • 30 citations

Resonance Raman studies of hemerythrin-ligand complexes

1975 • 30 citations

Studies on a possible reaction intermediate of -hydroxyphenylpyruvate dioxygenase

1975 • 29 citations

Raman spectrum of protocatechuate dioxygenase from Pseudomonas putida new low frequency bands

1979 • 28 citations

Photoinduced reactions. XXXI. Photooxidative ring-cleavage of dihydric phenols as possible models for biological oxygenation

1969 • 28 citations

Biogenetic type conversion of -hydroxyphenylpyruvic acid into homogentisic acid

1975 • 28 citations

Recent Studies on the Centrally Active Endogenous Amines

1963 • 27 citations

Substrate specificity of p-hydroxyphenylpyruvate hydroxylase

1972 • 27 citations

Oxygenation of 3-aryl-2-hydroxyacrylic acids. The question of linear fragmentation vs. cyclization and cleavage of intermediates

1978 • 24 citations

Interaction of protocatechuate-3,4-dioxygenase with fluoro-substituted hydroxybenzoic acids and related compounds

1978 • 24 citations

Extradiol Cleavage of 3-Methylcatechol by Catechol 1,2-Dioxygenase from Various Microorganisms

1977 • 23 citations

Fluorescence perturbation in soybean lipoxygenase‐1

1975 • 23 citations

Dioxygen fixation. Oxene transfer in the reaction of singlet dioxygen with .alpha.-keto acids

1978 • 19 citations

Extradiol cleavage of o-aminophenol by pyrocatechase

1978 • 19 citations

Circular dichroism of protocatechuate 3,4-dioxygenase from Pseudomonas aeruginosa

1975 • 18 citations

Acyl migration in the acid-catalyzed decomposition of .alpha.-hydroperoxy ketones

1978 • 18 citations

Base Catalyzed Oxygenation of 3,5-Di-t-butylpyrocatechol and Its Related Compounds

1974 • 17 citations

Studies on Oxygenases

1969 • 17 citations

Studies on the reaction intermediate of protocatechuate 3,4-dioxygenase Formation of enzyme-product complex

1978 • 16 citations

.beta. Scission of acyl radicals in the radical decomposition of various .alpha.-hydroperoxy ketones

1976 • 15 citations

Protocatechuate 3,4-dioxygenase. Resonance Raman studies of the oxygenated intermediate

1979 • 14 citations

Treatment of tetraethyl lead manufacturing wastes

1967 • 13 citations

Chemiluminescence during lipoxygenase-catalysed oxygenation of linoleic acid

1977 • 12 citations

Spin Relaxation in Magnetically Ordered (Salen)(Pyrrolidinedithiocarbamato)Fe(III)

1971 • 12 citations

Iron binding ligands in the catalytic site of protocatechuate 3,4-dioxygenase

1978 • 11 citations

Structure-volume relationships: volume effects produced by the interaction of Cu(II) with dipeptides

1978 • 9 citations

The participation of a tryptophan residue in the binding of ferric iron to pyrocatechase

1973 • 7 citations