Dopamine agonists: structure-activity relationships

Multiple receptors for dopamine

1979 • 3,739 citations

HEPATOCELLULAR CARCINOMA AND HEPATITIS B VIRUS

1981 • 2,891 citations

Conformational analysis—CI

1974 • 974 citations

Two dopamine receptors: Biochemistry, physiology and pharmacology

1984 • 939 citations

Conformational Analysis.

1966 • 696 citations

The central effects of a novel dopamine agonist

1978 • 646 citations

Catecholamines: Basic and clinical frontiers

1981 • 458 citations

Dopaminergic behaviour stereospecifically promoted by the D1 agonist R-SK & F 38393 and selectively blocked by the D1 antagonist SCH 23390

1984 • 351 citations

Ergot Alkaloids and Related Compounds

1978 • 319 citations

Dopamine is a monoamine oxidase B substrate in man

1977 • 313 citations

Progress in prolactin physiology and pathology

1978 • 277 citations

Dopamine receptors: Selective agonists and antagonists of functionally distinct types within the feline brain

1976 • 234 citations

Central dopamine receptor agonist and antagonist actions of the enantiomers of 3-PPP

1983 • 200 citations

Differentiation of the dopamine mechanisms mediating stereotyped behaviour and hyperactivity in the nucleus accumbens and caudate-putamen

1977 • 179 citations

ET495 and brain catecholamine mechanisms: Evidence for stimulation of dopamine receptors

1972 • 176 citations

Bicyclic and tricyclic ergoline partial structures. Rigid 3-(2-aminoethyl)pyrroles and 3- and 4-(2-aminoethyl)pyrazoles as dopamine agonists

1980 • 170 citations

Biochemical evidence for the 5-HT agonist properties of PAT (8-hydroxy-2-(di-n-propylamino)tetralin) in the rat brain

1984 • 168 citations

The dopamine receptor: Differential binding of d-LSD and related agents to agonist and antagonist states

1975 • 165 citations

Evidence for a new type of dopamine receptor stimulating agent

1971 • 152 citations

Effects of dopamine-like drugs on rat striatal adenyl cyclase have implications for CNS dopamine receptor topography

1974 • 151 citations

Direct dopaminergic action of lisuride hydrogen maleate, an ergot derivative, in mice

1976 • 144 citations

TREATMENT OF PARKINSONISM WITH BROMOCRIPTINE

1974 • 137 citations

Partialsynthese von Alkaloiden vom Typus des Ergobasins. (6. Mitteilung über Mutterkornalkaloide)

1943 • 137 citations

Synthesis and pharmacology of some 2-aminotetralins. Dopamine receptor agonists

1975 • 134 citations

Activity of two new potent dopaminergic agonists at the striatal and anterior pituitary levels

1980 • 122 citations

Resolution and absolute configuration of an ergoline-related dopamine agonist, trans-4,4a,5,6,7,8,8a,9-octahydro-5-propyl-1H(or 2H)-pyrazolo[3,4-g]quinoline

1983 • 121 citations

Nomifensine: A potent dopaminergic agonist of antiparkinson potential

1975 • 107 citations

Quantum mechanical study of the conformational properties of phenethylamines of biochemical and medicinal interest

1972 • 105 citations

Effects of (8β)-8-[(Methylthio)methyl]-6-propylergoline on dopaminergic function and brain dopamine turnover in rats

1979 • 104 citations

Bromocriptine: A Clinical and Pharmacological Review

1981 • 101 citations

Effects of B‐HT 920 and B‐HT 933 on Dopamine and Noradrenaline Autoreceptors in the Rat Brain

1983 • 101 citations

Studies on the sulphation of 3,4-dihydroxyphenylethylamine (dopamine) and related compounds by rat tissues

1973 • 98 citations

Para-O-Methylation of Dopamine in Schizophrenic and Normal Individuals

1964 • 96 citations

Cerebral dopamine agonist properties of some 2-aminotetralin derivatives after peripheral and intracerebral administration

1977 • 94 citations

3-Phenylpiperidines. Central dopamine-autoreceptor stimulating activity

1981 • 90 citations

Design of agents for stimulation of neostriatal dopaminergic mechanisms

1974 • 90 citations

Dopamine receptor agonistic and antagonistic effects of 3-PPP enantiomers

1983 • 90 citations

Piribedil and apomorphine: pre- and postsynaptic effects on dopamine synthesis and neuronal activity.

1975 • 89 citations

Dopamine receptors explained

1982 • 88 citations

Metabolism and storage of biogenic amines

1957 • 88 citations

N-Methylation of Dopamine to Epinine in Brain Tissue using N-Methyltetrahydrofolic Acid as the Methyl Donor

1972 • 88 citations

Pharmacologic Effects in Man of a Potent, Long-Acting Dopamine Receptor Agonist

1979 • 86 citations

Neurochemical and Behavioral Evidence for a Selective Presynaptic Dopamine Receptor Agonist

1980 • 85 citations

Drugs affecting the central nervous system

2023 • 84 citations

THE IONIZATION OF PHENOLIC AMINES, INCLUDING APOMORPHINE, DOPAMINE AND CATECHOLAMINES AND AN ASSESSMENT OF ZWITTERION CONSTANTS

1976 • 82 citations

Synthesis and dopaminergic activity of (+-)-, (+)-, and (-)-2-dipropylamino-5-hydroxy-1,2,3,4-tetrahydronaphthalene

1976 • 82 citations

The effect of trivastal, haloperidol and dibutyryl cyclic AMP on [14C]dopamine synthesis in rat striatum

1973 • 81 citations

Absolute stereochemistry and dopaminergic activity of enantiomers of 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine

1982 • 80 citations

Progress in prolactin physiology and pathology

1980 • 78 citations

N-Alkylated 2-aminotetralins: central dopamine-receptor stimulating activity

1979 • 76 citations

Pharmacological and Biochemical Evidence for the Existence of Two Categories of Dopamine Receptor

1984 • 76 citations

Resolved 3-(3-Hydroxyphenyl)-N-n-propylpiperidine and its analogs: central dopamine receptor activity

1984 • 74 citations

Studies on renal dopamine receptors with a new agonist

1978 • 73 citations

Separation of potent central and renal dopamine agonist activity in substituted 6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepines

1980 • 73 citations

Proceedings from the Symposium

2008 • 72 citations

Pharmacologic profile of a novel potent direct-acting dopamine agonist, (+)-4-propyl-9-hydroxynaphthoxazine [(+)-PHNO].

1984 • 72 citations

Comparative neuropharmacology of buspirone and MJ-13805, a potential anti-anxiety drug

1983 • 71 citations

A comparison of circling models for the detection of antiparkinson activity

1975 • 67 citations

N,N-disubstituted 2-aminotetralins are potent D-2 dopamine receptor agonists

1984 • 67 citations

Buspirone: chemical profile of a new class of anxioselective agents.

1982 • 66 citations

Pharmacological profiles of the putative dopamine autoreceptor agonists 3-PPP and TL-99

1981 • 62 citations

INHIBITION OF PROLACTIN SECRETION BY LERGOTRILE MESYLATE: MECHANISM OF ACTION

1975 • 61 citations

Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines

1982 • 60 citations

Synthesis of 4-substituted 2H-naphth[1,2-b]-1,4-oxazines, a new class of dopamine agonists

1984 • 59 citations

Does sulfate conjugation contribute to the metabolic inactivation of catecholamines in humans?

1982 • 58 citations

The site and mode of action of ET495 for the mediation of stereotyped behaviour in the rat

1973 • 58 citations

Preliminary investigation of the metabolism of piribedil (ET 495); a new central dopaminergic agonist and potential anti-parkinson agent

1973 • 57 citations

Centrally acting emetics. 9. Hofmann and Emde degradation products of nuciferine

1975 • 56 citations

Synthesis, resolution, absolute stereochemistry, and enantioselectivity of 3',4'-dihydroxynomifensine

1984 • 54 citations

Centrally acting emetics. 5. Preparation and pharmacology of 10-hydroxy-11-methoxyaporphine (Isoapocodeine). In vitro enzymic methylation of apomorphine

1972 • 54 citations

Synthesis and pharmacology of centrally acting dopamine derivatives and analogs in relation to Parkinson's disease

1973 • 54 citations

Effects on the Central Nervous System

1978 • 54 citations

Aporphines. 8. Total Synthesis and Pharmacological Evaluation of (±)-Apomorphine, (±)-Apocodeine, (±)-N-n-Propylnorapomorphine, and (±)-N-n--Propylnorapocodeine

1973 • 54 citations

Photochemistry of diazonium salts. 4. Synthesis of ring-fluorinated tyramines and dopamines

1976 • 54 citations

Effects of a potent dopamine receptor agonist, RDS-127, on penile reflexes and seminal emission in intact and spinally transected rats

1982 • 53 citations

Effects of a novel dopamine-receptor agonist RDS-127 (2-N,N-di-n-propylamino-4,7-dimethoxyindane), on hormone levels and sexual behavior in the male rat

1982 • 53 citations

Stereoisomers of apomorphine differ in affinity and intrinsic activity at presynaptic dopamine receptors modulating [3H]dopamine and [3H]acetylcholine release in slices of cat caudate

1983 • 51 citations

Differential activation by some 2-aminotetralin derivatives of the receptor mechanisms in the nucleus accumbens of rat which mediate hyperactivity and stereotyped biting

1977 • 51 citations

Comparison of structural and stereoisomers of apomorphine on stereotyped sniffing behavior of the rat

1975 • 51 citations

Actions of dopaminergic agonists on motor function.

1975 • 50 citations

A pharmacological comparison of 6,7-dihydroxy-2-dimethylaminotetralin (TL-99) and N-n-propyl-3-(3-hydroxyphenyl)piperidine with (3-PPP) selected dopamine agonists.

1982 • 50 citations

Behavioural evidence of dopamine receptor stimulation by piribedil (ET495) and its metabolite S584

1974 • 49 citations

N,N-Di-n-propyl dopamine: a qualitatively different dopamine vascular agonist.

1978 • 49 citations

(3,4-Dihydroxy-phenylamino)-2-imidazoline (DPI), a new potent agonist at dopamine receptors mediating neuronal inhibition

1975 • 49 citations

The effects of SCH 23390, YM 09151-2, (+)- and (−)-3-PPP and some classical neuroleptics on D-1 and D-2 receptors in rat neostriatum in vitro

1984 • 48 citations

Structure activity relationships of N-substituted dopamine derivatives as agonists of the dopamine vascular and other cardiovascular receptors.

1980 • 48 citations

Effect of 8-hydroxy-2-(di-n-propylamino) tetralin on rat prolactin secretion

1984 • 48 citations

SCH 23390 blocks D-1 and D-2 dopamine receptors in rat neostriatum in vitro

1984 • 48 citations

Is TL-99 a selective presynaptic dopamine receptor agonist?

1982 • 47 citations

Synthesis and biological activity of (6aS)-10,11-dihydroxyaporphine, the optical antipode of apomorphine

1973 • 46 citations

Long lasting stimulation of locomotor activity produced by the intraventricular injection of a cyclic analogue of dopamine into conscious mice

1974 • 46 citations

Proposed dopaminergic pharmacophore of lergotrile, pergolide, and related ergot alkaloid derivatives

1981 • 46 citations

Evidence that dopamine is a neurotransmitter in peripheral tissues

1983 • 45 citations

N-Methylation of biogenic amines—I

1974 • 45 citations

An efficient resolution of 3-PPP and assignment of the absolute configuration.

1983 • 45 citations

Script: interactive molecular geometrical treatments on the basis of computer-drawn chemical formula

1981 • 45 citations

Aporphines 15 action of aporphine alkaloids on dopaminergic mechanisms in rat brain

1976 • 45 citations

Centrally acting emetics. 6. Derivatives of .beta.-naphthylamine and 2-indanamine

1972 • 44 citations

Aporphines. 11. Synthesis and dopaminergic activity of monohydroxyaporphines. Total synthesis of (+-)-11-hydroxyaporphine, (+-)-11-hydroxynoraporphine, and (+-)-11-hydroxy-N-propylnoraporphine

1974 • 42 citations

Dopamine 3-O-sulphate, an end product of L-dopa metabolism in Parkinson patients

1974 • 42 citations

Molecular characteristics of biogenic monoamines and their analogs

1973 • 42 citations

Prolonged apomorphine-like behavioural effects of apomorphine esters

1976 • 41 citations

The separation and identification of dopamine 3-O-sulfate and dopamine 4-O-sulfate in urine of Parkinsonian patients.

1975 • 41 citations

Synthesis of 2-(alkylamino)-5,6- and -6,7-dihydroxy-3,4-dihydroquinazolines and evaluation as potential dopamine agonists

1982 • 39 citations

Structural correlation between apomorphine and LSD: Involvement of dopamine as well as serotonin in the actions of hallucinogens

1976 • 39 citations

In vivo dopamine autoreceptor selectivity appears to be critically dependent upon the aromatic hydroxyl position in a series of N,N-disubstituted 2-aminotetralins

1984 • 39 citations

Über die absolute Konfiguration des Morphins und verwandter Alkaloide

1955 • 38 citations

Centrally acting emetics. II. Norapomorphine and derivatives

1968 • 38 citations

Deamination of dopamine and its 3-O-methylated derivative by human brain monoamine oxidase

1978 • 38 citations

Rigid congeners of dopamine based on octahydrobenzo[f]quinoline: peripheral and central effects

1979 • 38 citations

Preparation and biological actions of some symmetrically N,N-disubstituted dopamines

1978 • 37 citations

Cholinergic effects of molecular segments of apomorphine and dopaminergic effects of N,N-dialkylated dopamines

1975 • 37 citations

Further studies on alterations in male rat copulatory behavior induced by the dopamine-receptor agonist RDS-127

1983 • 36 citations

Optical rotatory dispersion and absolute configuration—II

1965 • 36 citations

Conformational requirements for dopamine-induced vasodilation.

1977 • 36 citations

Electrophysiological studies on EMD 23 448, an indolyl-3-butylamine, in the rat: A putative selective dop amine autoreceptor agonist

1983 • 35 citations

The crystal and molecular structure of apomorphine hydrochloride hydrate

1973 • 35 citations

cis Addition of Performic Acid to Indene and Nuclear Magnetic Resonance Spectra of 1,2-Disubstituted Indanes

1964 • 35 citations

Effect of non-catecholic 2-aminotetralin derivatives on dopamine metabolism in the rat striatum

1980 • 34 citations

Aporphines. 21. Dopaminergic activity of aporphine and benzylisoquinoline derivatives. Synthesis of 8-hydroxyaporphines and 1-(hydroxybenzyl)-2-n-propyl-1,2,3,4-tetrahydroisoquinolines

1977 • 34 citations

Biological Disposition of Apomorphine III

1961 • 33 citations

Monophenolic 2-(dipropylamino)indans and related compounds: central dopamine-receptor stimulating activity

1981 • 33 citations

Monophenolic octahydrobenzo[f]quinolines: central dopamine- and serotonin-receptor stimulating activity

1982 • 33 citations

Aporphines. 9. Synthesis and Pharmacological Evaluation of (±) 9, 10-Dihydroxyaporphine [(±)-Isoapomorphine], (±)-,(-)-, and (±)-1,2-Dihydroxyaporphine, and (+)-1, 2, 9, 10 - Tetrahydroxyaporphine.

1973 • 33 citations

The 6-hydroxydopamine rotational model for the detection of dopamine agonist activity: reliability of effect from different locations of 6-hydroxydopamine

1975 • 33 citations

Conformationally restricted congeners of dopamine derived from 2-aminoindan

1982 • 33 citations

O-methylation of apomorphine and the metabolic prolongation of apomorphine-induced stereotyped behaviour

1973 • 32 citations

Dopaminergic prodrugs: Brain concentrations and neurochemical effects of 5,6- and 6,7-ADTN after administration as dibenzoyl esters

1980 • 32 citations

Conformational analysis of dopamine by the INDO molecular orbital method

1977 • 32 citations

Biological Disposition of Apomorphine II

1961 • 32 citations

EFFECTS OF ERGOLINES ON DOPAMINERGIC AND SEROTONERGIC SINGLE UNIT ACTIVITY

1979 • 32 citations

Die Konfiguration des Apomorphins und verwandter Verbindungen

1955 • 31 citations

Centrally acting emetics. 10. Rigid dopamine congeners derived from octahydrobenzo[f]quinoline

1976 • 30 citations

Aporphines. 48. Enantioselectivity of (R)-(-)- and (S)-(+)-N-n-propylnorapomorphine on dopamine receptors

1983 • 30 citations

Synthesis and biological activity of some aporphine derivatives related to apomorphine

1974 • 30 citations

Behavioral effects of apomorphine and diisobutyrylapomorphine in the mouse

1977 • 30 citations

RDS-127 (2-di-n-propylamino-4,7-dimethoxyindane): central effects of a new dopamine receptor agonist.

1983 • 29 citations

Conformational analogs of dopamine. Synthesis and pharmacological activity of (E)- and (Z)-2-(3,4-dihydroxyphenyl)cyclopropylamine hydrochlorides

1979 • 29 citations

A comparison of dopamine agonist action to inhibit locomotor activity and to induce stereotyped behaviour in the mouse

1984 • 29 citations

Drugs Affecting the Central Nervous System

2020 • 29 citations

LY 141865 stimulates histamine-2 (H2) receptors and dopamine-2 (DA2 receptors in the anaesthetised dog

1983 • 29 citations

Emetic activity of N-substituted norapomorphines

1975 • 29 citations

ENANTIOSELECTIVITY IN THE BINDING OF (+)- AND (−)-2-AMINO-6,7-DIHYDROXY-1,2,3,4-TETRAHYDRONAPHTHALENE AND RELATED AGONISTS TO DOPAMINE RECEPTORS

1979 • 28 citations

Evidence for the methylation of apomorphine by catechol-O-methyl-transferase in vivo and in vitro

1973 • 28 citations

Chemische Bestimmung der absoluten Konfiguration der Lysergsäure 54. Mitteilung über Mutterkornalkaloide

1962 • 28 citations

The significance of COMT activity in controlling dopamine agonist levels in brain and serum: Studies with a prodrug and a metabolite of 6,7-ADTN

1980 • 27 citations

Behavioral effects of (−)10, 11-methylenedioxy-n-n-propylnoraporphined, an orally effective long-acting agent active at central dopamine receptors, and analogous aporphines

1982 • 27 citations

6-Hydroxy-4-[2-di-n-propylaminoethyl]indole: synthesis and dopaminergic actions

1984 • 27 citations

Induction and Inhibition of In Vivo Glucuronidation of Apomorphine in Mice

1971 • 27 citations

Congeners of the .beta. conformer of dopamine derived from cis- and trans-octahydrobenzo[f]quinoline and trans-octahydrobenzo[g]quinoline

1980 • 27 citations

Comparison of biological effects of N-alkylated congeners of .beta.-phenethylamine derived from 2-aminotetralin, 2-aminoindan, and 6-aminobenzocycloheptene

1980 • 26 citations

Chemical Background

1978 • 26 citations

The convulsive effects of dopamine sulfate conjugates in rat brain

1981 • 26 citations

The binding of fluorocatecholamines to adrenergic and dopaminergic receptors in rat brain membranes

1980 • 25 citations

Direct effect of a nomifensine derivative on dopamine receptors

1978 • 25 citations

Pharmacology of Nomifensine

1982 • 25 citations

4-(Aminoalkyl)-7-hydroxy-2(3H)-indolones, a novel class of potent presynaptic dopamine receptor agonists

1983 • 25 citations

Conformation of dopamine at the dopamine receptor.

1978 • 25 citations

Dopaminergic effects of non-hydroxylated rigid analogs of apomorphine

1979 • 25 citations

N-0434, a very potent and specific new D-2 dopamine receptor agonist

1984 • 25 citations

An orally effective, long-acting dopaminergic prodrug: (−)-10,11-methylenedioxy-N-propylnoraporphine

1982 • 24 citations

.alpha.-Adrenergic agents. 2. Synthesis and .alpha.1-agonist activity of 2-aminotetralins

1982 • 24 citations

Central antidopaminergic properties of 2-bromolisuride, an analogue of the ergot dopamine agonist lisuride

1983 • 22 citations

2-Amino-4,7-dimethoxyindan derivatives: synthesis and assessment of dopaminergic and cardiovascular actions

1982 • 22 citations

Sulfate Conjugation of Dopamine in Rat Brain: Regional Distribution of Activity and Evidence for Neuronal Localization

1984 • 21 citations

Esters of apomorphine and N,N-dimethyldopamine as agonists of dopamine receptors in the rat brain in vivo

1975 • 21 citations

Derivatives of 5-hydroxy-6-methyl-2-aminotetralin

1980 • 20 citations

Effects of ring fluorination on the cardiovascular actions of dopamine and norepinephrine in the dog.

1980 • 20 citations

Inhibition of the sympathetic nervous system by a series of heterocyclic congeners of dopamine.

1976 • 20 citations

Dopamine 3-sulfate inhibits aldosterone secretion in cultured bovine adrenal cells

1984 • 20 citations

Congeners of the .alpha. conformer of dopamine derived from octahydrobenz[h]isoquinoline

1980 • 20 citations

Effect of piribedil and one of its metabolites on the concentration of homovanillic acid in the rat brain

1974 • 20 citations

Biological Disposition of Rigid Analogs of Amphetamine

1977 • 20 citations

Synthesis and central dopaminergic activities of (.+-.)-hexahydro-4H-indolo[3,4-gh][1,4]benzoxazine derivatives [(.+-.)-9-oxaergolines]

1983 • 19 citations

Stereochemistry of 1,3-cyclohexadienes. Conformational preferences in 9-substituted 9,10-dihydrophenanthrenes

1976 • 19 citations

Metabolism of lergotrile to 13-hydroxy lergotrile, a potent inhibitor of prolactin release in vitro

1978 • 19 citations

The effects of dopamine, piribedil (ET-495) and its metabolite S-584 on retinal adenylate cyclase

1975 • 19 citations

Nuclear magnetic resonance studies of catecholamines. Complex formation with adenosine 5'-triphosphate in aqueous solution. Stoichiometry and molecular conformations

1978 • 18 citations

Comparative effects of benztropine and nomifensine on dopamine uptake and release from striatal synaptosomes

1981 • 18 citations

Dopaminergic agonists: comparative actions of amine and sulfonium analogs of dopamine

1984 • 18 citations

Effect of catechol-O-methyltransferase inhibitors on brain apomorphine concentrations and stereotyped behaviour in the rat

1975 • 18 citations

Synthesis and dopaminergic activity of (R)- and (S)-4-hydroxy-2-(di-n-propylamino)indan

1985 • 18 citations

Interaction of apomorphine, neuroleptics and stimulants with α-methyl-m-tyramine, a false dopaminergic transmitter

1974 • 18 citations

Modification of cardiovascular actions of 2-amino-5,6-dihydroxytetralin by N,N-Di-n-propyl substitution

1982 • 17 citations

Rigid analogs of dopamine: synthesis and interaction of 6-exo- and 6-endo-(3',4'-dihydroxyphenyl)-2-azabicyclo[2.2.2]octanes with dopamine uptake sites and receptors

1982 • 17 citations

Synthesis of (7R)-7H-indolo[3,4-gh][1,4]benzoxazines, a new class of D-heteroergolines with dopamine agonist activity

1983 • 17 citations

Synthesis and Dopaminergic Activity of 3-(3,4-Dihydroxyphenyl)-1-n-propylpyrrolidine Hydrobromide

1984 • 16 citations

Conformationally restricted congeners of dopamine derived from octahydrobenzo[g]quinoline and octahydrobenzo[f]quinoline

1984 • 16 citations

PRODRUGS OF SOME DOPAMINERGIC 2-AMINOTETRALINS - A REVIEW OF THEIR SYNTHESES AND NEUROCHEMICAL PROFILES

1980 • 15 citations

N-Alkyl derivatives of (.+-.)-.alpha.-methyldopamine

1979 • 15 citations

Synthesis and dopaminergic properties of some exo- and endo-2-aminobenzonorbornenes designed as rigid analogs of dopamine

1982 • 15 citations

B-HT 958 stimulates dopamine autoreceptors but blocks noradrenaline autoreceptors in the brain

1984 • 15 citations

Conversion of ergolines to hexahydro- and octahydrobenzo[f]quinolines (depyrroloergolines)

1980 • 14 citations

Centrally Acting Emetics. III. Derivatives of beta-Naphthylamine

1969 • 14 citations

5,7-Dihydroxy-2-aminotetralin derivatives: synthesis and assessment of dopaminergic and adrenergic actions

1981 • 14 citations

Hypotensive Effects of N,N Di-n-propyldopamine in the Anesthetized Dog

1980 • 14 citations

Demonstration of N-acetyldopamine in human kidney and urine

1984 • 14 citations

Profil psychopharmacologique d'un nouvel agoniste Dopaminergique, le RU 24213

1980 • 14 citations

(±)-(E)-2-(3,4-Dihydroxyphenyl)cyclopropylamine hydrochloride(ASL-7003): a rigid analogue of dopamine

1978 • 14 citations

Potent dopamine agonist activity of a novel ergoline, 6-Ethyl-9-oxaergoline (EOE)

1982 • 14 citations

New selenium-75 labeled radiopharmaceuticals: selenonium analogs of dopamine

1983 • 14 citations

The bicuculline - like properties of dopamine sulfate in rat brain

1984 • 13 citations

Norepinephrine uptake sites in cardiac tissue. Lack of affinity of 6-hydroxynorepinephrine and related compounds

1975 • 13 citations

Synthesis and dopamine receptor binding of exo- and endo-2-amino-6,7-dihydroxybenzonorbornene, rigid analogs of 2-amino-6,7-dihydroxytetrahydronaphthalene

1982 • 13 citations

Ergot alkaloids. 87. New ergolines as selective dopaminergic stimulants

1978 • 13 citations

N-Allylnorapomorphine^1a

1965 • 12 citations

Unequivocal synthesis and characterisation of dopamine 3- and 4-O-sulphates

1982 • 12 citations

6,7-Dihydroxy-3-chromanamine: synthesis and pharmacological activity of an oxygen isostere of the dopamine agonist

1984 • 12 citations

Comparative study of central dopaminergic properties of RU 29717 (N-propyl-9-oxaergoline) and pergolide

1983 • 12 citations

Abnormal O-methylated dopamine metabolites: The endogenous toxins of schizophrenia or parkinsonism?

1973 • 12 citations

3‐(2‐Dipropylamino‐äthyl)‐phenol, ein neuer, selektiver dopaminerger Agonist

1977 • 12 citations

C(2)-Methylation abolishes DA1 dopamine agonist activity of 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (6,7-ADTN): steric intolerance by the receptor

1984 • 12 citations

A potential anti-Parkinson drug, N-n-propyl-N-n-butyl-.beta.-(3,4-dihydroxyphenyl)ethylamine hydrochloride, and its effects in intact and nigra-lesioned rats

1978 • 12 citations

The absolute configuration of apomorphine

1977 • 11 citations

The purported dopamine agonist DPI inhibits [3H]noradrenaline release from rat cortical slices but not [3H]dopamine and [14C]acetylcholine release from rat striatal slices in-vitro

1983 • 11 citations

Topographical Model of the Renal Vascular Dopamine Receptor

1980 • 11 citations

C1-Methylated 5-hydroxy-2-(dipropylamino)tetralins: central dopamine-receptor stimulating activity

1984 • 11 citations

Conformations and biological properties of apomorphine and its phenanthro [10, 1-b, c] azepine homologue

1975 • 11 citations

Centrally acting emetics. 8. Conformational aspects of certain dihydrophenanthrene congeners of apomorphine

1975 • 11 citations

Centrally acting emetics. 7. Hofmann and Emde degradation products of apomorphine

1973 • 11 citations

The NMR spectra of some 2-substituted indanes and their tricarbonylchromium complexes

1965 • 11 citations

Studies on the dopamine agonist properties of 8-amino-2-methyl-4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline, a derivative of nomifensine

1978 • 11 citations

The hydroxy-hexanydronaphthoxazines: a new group of very potent and selective dopamine agonists

1984 • 11 citations

Effects of 3′,4′-dihydroxynomifensine on the dopamine vascular receptor

1980 • 10 citations

SYNTHESIS AND ACTIVITY OF A METABOLITE OF THE DOPAMINERGIC AGONIST 6,7-ADTN

1981 • 10 citations

Lack of effect of ibopamine, a dopamine pro‐drug, on renal function in normal subjects.

1984 • 10 citations

Effects of dextro-amphetamine on the incorporation of carbon atoms of D-mannose into the brains and sera of differentially housed mice: short-term reversibility of these effects.

1973 • 9 citations

Reinvestigation of the Biological Activities of Diacetylapomorphine and "Triacetylapomorphine"

1963 • 9 citations

Structural Analogues Of Aporphines Part 1: Synthesis of Apomorphines with the Catechol Moiety Replaced by 5‐membered Heterocycles

1982 • 9 citations

Synthese und pharmakologische Eigenschaften von silylierten Dopaminen und 4.4-Diphenylpiperidinen/Synthesis and Pharmacological Properties of Silylated Dopamines and 4,4-Diphenylpiperidines

1983 • 9 citations

New dopaminergic and potential anti-Parkinson compounds, N,N-disubstituted .beta.-(3,4-dihydroxyphenyl)ethylamines

1978 • 9 citations

(3,4-Dihydroxyphenylimino)-2-imidazoline (DPI): a stimulant of α-adrenoceptors and dopamine receptors

1984 • 8 citations

1-(Aminomethyl)-6,7-dihydroxytetralin derivatives: synthesis and assessment of dopamine-like effects

1983 • 8 citations

Dopamine vascular actions of N-substituted derivatives of 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (ADTN)

1979 • 8 citations

Effects of S (+)-3-phenethyl-PP, a putative dopamine autoreceptor agonist with greater autoreceptor selectivity than 3-PPP enantiomers

1984 • 7 citations

Dopaminergic agonist Ro 8-4650 in Parkinson's disease

2009 • 7 citations

The effect of hydrogen ion concentration on the precipitating and protective actions of proteins on colloidal gold and gum benzoin

1931 • 7 citations

Resorcinol congeners of dopamine derived from benzocycloheptene and indan

1984 • 7 citations

A new class of D-heteroergolines: total synthesis and resolution of a 9-oxaergoline, 4,6,6a,8,9,10a-hexahydro-7-ethyl-7H-indolo[3,4-gh][1,4]benzoxazine

1982 • 7 citations

Conformationally restricted dopamine congeners—a molecular mechanics-based study

1983 • 7 citations

Systemic hemodynamic and regional blood flow effects of LY141865, a selective dopamine receptor agonist.

1984 • 7 citations

Comparison of the Cardiovascular Actions of N, N-Di-n-Propyl Dopamine and Sodium Nitroprusside in Conscious and Chloralose-Anaesthetised Dogs

1982 • 7 citations

The metabolism of dopamine, NN-dialkylated dopamines and derivatives of the dopamine agonist 2−amino-dihydroxy−1,2,3,4−tetrahydronaphthalene (ADTN) by catechol-O-methyltransferase

1984 • 7 citations

5,6- and 6,7-dihydroxyspiro (tetralin-1,3'-pyrrolidine): conformationally restricted analogues of dopamine.

1980 • 7 citations

Dopamine agonistic potency of two novel prolactin release-inhibiting ergolines

1984 • 7 citations

O-methylation of dopamine-0-sulfates with cathechol-0-methyltransferase

1983 • 6 citations

Alkylation of ergoline derivatives at position N(1)

1982 • 6 citations

Interaction of the component enantiomers of the putative dopamine autoreceptor agonist, TL-99 (6,7-dihydroxy-2-dimethylamino tetralin) with dopaminergic systems in mammalian brain and teleost retina

1983 • 6 citations

Troponoid. V. Crystallographic studies on AY-27110 — a dopamine agonist of the troponylpiperazine series

1982 • 6 citations

The crystal structure of (+)-2-dipropylamino-5-hydroxytetralin hydrochloride

1980 • 6 citations

Biochemical characterization of the enantiomers of the novel ergoline dopamine agonist 6‐ethyl‐9‐oxaergoline (EOE)

1983 • 6 citations

Analysis of the cardiac stimulant properties of (3,4-dihydroxyphenyl)-cyclopropylamine (ASL-7003) and 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (A6,7DTN).

1979 • 6 citations

Neurochemical and behavioural profiles of five dopamine analogues

1981 • 6 citations

6,7-Dihydroxy-2-dimethylaminotetralin (TL-99) stimulates postjunctional D-1 and D-2 dopamine receptors

1983 • 5 citations

Troponoids. 6. Troponylpiperazines: a new class of dopamine agonists

1984 • 5 citations

2-Formyl derivatives of 6-methylergoline-I

1982 • 5 citations

Catechol derivatives of 6-aminobenzocycloheptene: assessment of dopaminergic effects

1984 • 5 citations

Physiologic disposition of lergotrile

1978 • 5 citations

The behavioral pharmacology of Ay‐27,110, a novel nonergot dopaminergic agonist

1984 • 4 citations

Possible biologically active metabolites of 5-hydroxy-6-methyl-2-di--propylaminotetralin

1984 • 4 citations

Interactions of a partial ergoline with dopamine receptors in vivo and in vitro

1983 • 4 citations

Hypotensive action and alpha-adrenolytic properties of a new dopaminergic agonist, CU 32-085, in the rat.

1984 • 3 citations

6-Amino-6,7,8,9-tetrahydro-5H-benzocycloheptene and derivatives

1974 • 3 citations

cis- and trans-4-n-Propyl-1,2,3,4,4a,5,6, 10b-octahydrobenzo(f)quinolines

1985 • 3 citations

Dopamine receptor stimulating and alpha adrenoceptor blocking actions of trans (CS-265) and cis (CS-263) isomers of nonhydroxylated N-propyl octahydrobenzo[F]quinoline.

1984 • 2 citations

Evidence that a novel dopamine receptor agonist, RDS-127 [2−di-n-propylamino−4,7−dimethoxyindane] has some centrally mediated cardiovascular actions

1984 • 2 citations

The kinetics of the enzymatic O-methylation of catechols and catecholamines

1983 • 2 citations

Chapter 3. Antipsychotic Agents and Dopamine Agonists

1983 • 2 citations

Foreword

1982 • 2 citations

Trans-N-Alkyl-6, 7-Dihydroxyoctahydrobenzo[g]-Quinolines: Apomorphine Congeners Lacking the Non-Oxygenated Aromatic Ring

1981 • 1 citations

TL-350, an ergoline derivative with dopamine receptor agonist properties.

1984 • 1 citations

Deleted Work

1955 • 0 citations