Immune Response to Synthetic Herpes Simplex Virus Peptides:The Feasibility of a Synthetic Vaccine

Computed circular dichroism spectra for the evaluation of protein conformation

1969 • 3,654 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

Solid Phase Peptide Synthesis

1976 • 1,798 citations

Binding of immunogenic peptides to Ia histocompatibility molecules

1985 • 1,209 citations

T-cell antigenic sites tend to be amphipathic structures.

1985 • 527 citations

Monoclonal antibodies to herpes simplex virus type 1 proteins, including the immediate-early protein ICP 4

1981 • 436 citations

Construction of live vaccines using genetically engineered poxviruses: biological activity of vaccinia virus recombinants expressing the hepatitis B virus surface antigen and the herpes simplex virus glycoprotein D.

1984 • 287 citations

Herpes Simplex Virus Type-1 Glycoprotein D Gene: Nucleotide Sequence and Expression inEscherichia coli

1982 • 285 citations

Localization and synthesis of an antigenic determinant of herpes simplex virus glycoprotein D that stimulates the production of neutralizing antibody

1984 • 192 citations

Contribution of antigen-presenting cell major histocompatibility complex gene products to the specificity of antigen-induced T cell activation

1982 • 170 citations

Glycoprotein D protects mice against lethal challenge with herpes simplex virus types 1 and 2

1984 • 150 citations

Solid-Phase Peptide Synthesis

1976 • 117 citations

Synthetic glycoprotein D-related peptides protect mice against herpes simplex virus challenge

1985 • 114 citations

Purification of glycoprotein gD of herpes simplex virus types 1 and 2 by use of monoclonal antibody

1982 • 114 citations

The Ia molecule of the antigen-presenting cell plays a critical role in immune response gene regulation of T cell activation.

1983 • 105 citations

Protection of Mice from Lethal Herpes Simplex Virus Infection by Vaccination with a Secreted form of Cloned Glycoprotein D

1984 • 105 citations

Immunogenicity of a synthetic HBsAg peptide: Enhancement by conjugation to a fatty acid carrier

1984 • 102 citations

Effect of monoclonal antibodies on limited proteolysis of native glycoprotein gD of herpes simplex virus type 1

1982 • 96 citations

Glycoproteins of herpes simplex virus type 2 as defined by monoclonal antibodies

1982 • 92 citations

Protective immunization of mice with specific HSV-1 glycoproteins.

1983 • 90 citations

DNA sequence of the Herpes simplex virus type 2 glycoprotein D gene

1983 • 87 citations

DNA Sequence Analysis of the Type-Common Glycoprotein-D Genes of Herpes Simplex Virus Types 1 and 2

1984 • 77 citations

The T cell response to the glycoprotein D of the herpes simplex virus: the significance of antigen conformation.

1985 • 76 citations

Comparative structural analysis of glycoprotein gD of herpes simplex virus types 1 and 2

1980 • 63 citations

Fine structure analysis of type-specific and type-common antigenic sites of herpes simplex virus glycoprotein D

1984 • 57 citations

Genetic variation among influenza viruses

1981 • 57 citations

Correlation between the conformation of cytochrome c peptides and their stimulatory activity in a T-lymphocyte proliferation assay.

1983 • 56 citations

AN INFLUENZA IMMUNOSOME: ITS STRUCTURE AND ANTIGENIC PROPERTIES. A MODEL FOR A NEW TYPE OF VACCINE

1981 • 8 citations