Mammalian Metabolism of Flavonoids

The Flavonoids. A Class of Semi-Essential Food Components: Their Role in Human Nutrition

2015 • 1,500 citations

Gluconeogenesis in the perfused rat liver

1966 • 726 citations

A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compounds

1980 • 585 citations

Disposition of quercetin in man after single oral and intravenous doses

1975 • 392 citations

Mutagenic Activity of Quercetin and Related Compounds

1977 • 348 citations

Intestinal Bacteria And The Hydrolysis Of Glycosidic Bonds

1971 • 320 citations

Mutagenicity of plant flavonoids: Structural requirements for mutagenic activity in Salmonella typhimurium

1978 • 305 citations

Quercetin, a rat intestinal and bladder carcinogen present in bracken fern (Pteridium aquilinum).

1980 • 271 citations

Mutagenicity of plant flavonols in the Salmonella/mammalian microsome test

1979 • 238 citations

Metabolism of apigenin and related compounds in the rat. Metabolite formation in vivo and by the intestinal microflora in vitro

1972 • 228 citations

Studies on flavonoid metabolism

1971 • 199 citations

Mutagenicity of flavone derivatives.

1977 • 193 citations

Inhibition of lens aldose reductase by flavonoids—Their possible role in the prevention of diabetic cataracts

1976 • 190 citations

URINARY METABOLITES OF CAFFEIC AND CHLOROGENIC ACIDS

1957 • 188 citations

Alpha-Naphthoflavone: An Inhibitor of Hydrocarbon Cytotoxicity and Microsomal Hydroxylase

1969 • 185 citations

Fecalase: a model for activation of dietary glycosides to mutagens by intestinal flora.

1980 • 179 citations

Flavonoids as Inhibitors of Lens Aldose Reductase

1975 • 179 citations

Flavonoids and bioflavonoids

1996 • 177 citations

The Excretory Function of Bile

1977 • 172 citations

Metabolism of flavonoid compounds in germ-free rats

1972 • 165 citations

Metabolism of Phenolic Acids by the Rat Intestinal Microflora

1968 • 154 citations

Aryl hydrocarbon (benzo[a]pyrene) hydroxylases in liver from rats of different age, sex and nutritional status

1975 • 146 citations

Comparative mutagenesis of plant flavonoids in microbial systems

1978 • 145 citations

Induction of increased benzpyrene hydroxylase activity by flavones and related compounds.

1968 • 142 citations

THE METABOLIC FATE OF RUTIN AND QUERCETIN IN THE ANIMAL BODY

1956 • 138 citations

Comprehensive Biochemistry

1969 • 120 citations

Comparison of beta-naphthoflavone and 3-methylcholanthrene as inducers of hepatic cytochrome(s) P-448 and aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity.

1977 • 119 citations

The significance of equol in relation to the oestrogenic responses in sheep ingesting clover with a high formononetin content

1968 • 107 citations

METABOLIC FATE OF HESPERIDIN, ERIODICTYOL, HOMOERIODICTYOL, AND DIOSMIN

1958 • 97 citations

Metabolism of myricetin and related compounds in the rat. Metabolite formation in vivo and by the intestinal microflora in vitro

1972 • 91 citations

Mammalian metabolism of plant xenobiotics

1978 • 90 citations

Studies on flavonoid metabolism. Metabolism of (+)-[14C]catechin in the rat and guinea pig

1969 • 87 citations

Studies on flavonoid metabolism. Identification of the metabolities of (+)-catechin in rat urine

1964 • 83 citations

Flavonoids are selective cyclic GMP phosphodiesterase inhibitors

1979 • 83 citations

Liver as major organ of phenol detoxication?

1974 • 81 citations

Decarboxylation and demethylation of some phenolic benzoic acid derivatives by rat caecal contents

1966 • 80 citations

The Metabolism of Drugs and Other Organic Compounds by the Intestinal Microflora

1968 • 79 citations

Activation of carcinogens and mutagens by rat colon mucosa.

1978 • 69 citations

Mammalian metabolism of plant xenobiotics:

1979 • 66 citations

An in vitro study of formononetin and biochanin A metabolism in rumen fluid from sheep

1967 • 64 citations

Identification of products produced by the anaerobic degradation of rutin and related flavonoids by Butyrivibrio sp. C₃

1970 • 58 citations

Studies on flavonoid metabolism. Biliary and urinary excretion of metabolites of (+)-[U-14C]catechin

1971 • 55 citations

Glucuronide Decomposition in the Digestive Tract

1952 • 55 citations

Effect of quercetin on membrane-linked activities

1969 • 55 citations

Urinary products from quercetin in neomycin-treated rats

1965 • 54 citations

Identification of the major biliary metabolite of (+)-catechin in the rat

1980 • 54 citations

Metabolism of Oestrogenic Isoflavones in Sheep

1965 • 54 citations

Metabolic and Glucosuria Studies on Naringin and Phloridzin

1958 • 53 citations

Studies on flavonoid metabolism. Metabolism of (+)-catechin in the guinea pig

1968 • 53 citations

Topics in flavonoid chemistry and biochemistry

1976 • 49 citations

Anaerobic degradation of some bioflavonoids by microflora of the rumen

1969 • 46 citations

Metabolism of intraruminally administered [4-14C]formononetic and [4-14C]biochanin a in sheep

1971 • 43 citations

Synthesis and metabolic fate of hesperetin-3-14C

1976 • 42 citations

The biliary excretion of flavanones in the rat

1979 • 38 citations

The bacterial degradation of flavonoids. Hydroxylation of the A-ring of taxifolin by a soil pseudomonad

1972 • 38 citations

Differences in distribution of esterase between cell fractions of rat liver homogenates prepared in various media. Relevance to the lysosomal location of the enzyme in the intact cell

1971 • 34 citations

The formation of glucosides of isoflavones and of some other phenols by rabbit liver microsomal fractions

1972 • 33 citations

The metabolism of (+)-catechin to hydroxyphenylvaleric acids by the intestinal microflora

1970 • 33 citations

Metabolic studies of quercetin labeled with C14

1959 • 33 citations

Inhibition of human liver catechol-O-methyltransferase by flavonoids

1973 • 32 citations

Metabolism of the Hydroxyethylrutosides. II. Excretion and Metabolism of 3',4',7-Tri-O-(β-hydroxyethyl)rutoside and Related Compounds in Laboratory Animals after Parenteral Administration

1974 • 32 citations

Identification of products produced by the anaerobic degradation of naringin by Butyrivibrio sp. C₃

1971 • 32 citations

Studies on flavonoid metabolism. Degradation of (+)-catechin by rat intestinal contents

1969 • 32 citations

Metabolism of the Hydroxyethylrutosides Biliary and Urinary Excretion of 3′,4′,5-[Hydroxyethyl-¹⁴C], 7-Tetra-O-(β-Hydroxyethyl)-rutoside in Rats and Monkeys after Parenteral Administration

1972 • 32 citations

O-methylation in vitro of dihydroxy- and trihydroxy-phenolic compounds by liver slices

1962 • 28 citations

Ultraviolet Induction of Chromosome Transfer by Autonomous Sex Factors in Escherichia coli

1969 • 28 citations

The metabolism and acid degradation of quercetin

1959 • 27 citations

The bacterial degradation of flavonoids. Oxidative fission of the A-ring of dihydrogossypetin by a Pseudomonas sp

1972 • 26 citations

New oxygenases in the degradation of flavones and flavanones by Pseudomonas putida

1974 • 25 citations

The metabolism and excretion of 3-O-methyl-(+)-catechin in the rat, mouse, and marmoset.

1981 • 25 citations

Metabolism of the Hydroxyethylrutosides III. The Fate of Orally Administered Hydroxyethylrutosides in Laboratory Animals; Metabolism by Rat Intestinal Microflorain vitro

1974 • 24 citations

Preliminary studies on degradation products of quercetin in the rat's gastrointestinal tract

1959 • 22 citations

Studies on flavonoid metabolism. Excretion of m-hydroxyphenylhydracrylic acid from (plus)-catechin in the monkey (Macaca iris sp.).

1974 • 20 citations

The Disposition and Metabolism of 3',4',7-Tri-O-(β-hydroxyethyl) rutoside and 7-Mono-O-(β-hydroxyethyl)rutoside in the Mouse

1977 • 20 citations

O-(β-Hydroxyethyl)-rutoside—experimentelle und klinische Ergebnisse

1978 • 20 citations

Stimulation of mammalian epoxide hydrase activity by flavones

1980 • 19 citations

Contribution à l'étude d'un produit de β‐hydroxyéthylation du rutoside. Partie 2. Indentification des constituants majeurs par spectrophotométrie ultraviolette

1966 • 19 citations

Quantitative determination of 0-(β-hydroxyethyl)-rutosides in human blood after intravenous and oral administration by circular dichroism

1977 • 19 citations

Studies on flavonoid metabolism. Metabolism of flavone in the guinea pig

1966 • 18 citations

Identification of flavanone metabolites in rat urine by combined gas–liquid chromatography and mass spectrometry

1973 • 15 citations

THE MECHANISMS OF CATECHINS METABOLISM

1958 • 15 citations

3,5-Dihydroxyphenylpropionic acid, a further metabolite of sinapic acid

1970 • 15 citations

Identification of urinary metabolites of flavanone in the rat

1979 • 15 citations

m-Hydroxyphenylpropionic Acid, a Major Urinary Metabolite of (+)-Catechin in the Rat

1962 • 14 citations

Enterohepatic cycling of O-(β-hydroxyethyl) rutosides and their biliary metabolites in the rat

1977 • 14 citations

THE MECANISMS OF CATECHINS METABOLISM

1958 • 12 citations

The metabolism and excretion of 7-mono-0-(β-hydroxyethyl) rutoside in the dog

1979 • 11 citations

[Renal excretion of trihydroxy-ethylrutoside (Venoruton) after parenteral and oral administration].

1970 • 10 citations

Catechol-O-Methyltransferase, III. Beziehungen zwischen der Struktur von Flavonoiden und deren Eignung als Inhibitoren der CatechoI-O-Methyltransferase

1972 • 8 citations

Pharmacokinetics and disposition of orally administered [2,3-14C] succinimide in the rat

1978 • 7 citations

Spectrophotofluorometric Analysis of 3′,4′,7-Tris[O-(β-hydroxyethyl)]rutoside in Urine

1978 • 7 citations

(+)-Cyanidanol-3 as inhibitor of prostaglandin synthetase

1979 • 6 citations

Effects of flavonoid compounds on enzyme activities

1970 • 6 citations

Flavonoid sweeteners. Synthesis and intestinal absorption of selected sulfoalkylated hesperetin-3-14C derivatives in the rat

1978 • 6 citations

Resorption und Stoffwechsel von Hydroxyethylrutosiden

1978 • 5 citations

O-(β-Hydroxyethyl)-rutoside

1983 • 5 citations