Atrial Natriuretic Factor: A New Hormone of Cardiac Origin

A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats

1981 • 3,128 citations

Sodium ions, calcium ions, blood pressure regulation, and hypertension: a reassessment and a hypothesis

1977 • 1,317 citations

Atrial natriuretic factor—a circulating hormone stimulated by volume loading

1985 • 1,250 citations

Purification and complete amino acid sequence of α-human atrial natriuretic polypeptide (α-hANP)

1984 • 1,153 citations

初期食道静脈りゅう治療におけるテルイプレシン(グリプレシン)とバソプレシンの比較試験

1982 • 774 citations

The Heart and the Atrial Natriuretic Factor*

1985 • 763 citations

The amino acid sequence of an atrial peptide with potent diuretic and natriuretic properties

1983 • 743 citations

Bioactive Cardiac Substances: Potent Vasorelaxant Activity in Mammalian Atria

1983 • 711 citations

SPECIFIC GRANULES IN ATRIAL MUSCLE CELLS

1964 • 609 citations

Purification and Sequence Analysis of Bioactive Atrial Peptides (Atriopeptins)

1984 • 525 citations

Effects of auriculin (atrial natriuretic factor) on blood pressure, renal function, and the renin-aldosterone system in dogs

1984 • 522 citations

Studies on the efferent mechanism of the sodium diuresis which follows the administration of intravenous saline in the dog.

1961 • 507 citations

Atrial natriuretic factor elicits an endothelium-independent relaxation and activates particulate guanylate cyclase in vascular smooth muscle.

1984 • 495 citations

Circulatory Basis of Fluid Volume Control

1963 • 478 citations

PLASMA ATRIAL NATRIURETIC PEPTIDE IN CARDIAC DISEASE AND DURING INFUSION IN HEALTHY VOLUNTEERS

1985 • 471 citations

Endogenous digitalis-like substance in plasma of volume-expanded dogs

1980 • 444 citations

Inhibition of Aldosterone Production by an Atrial Extract

1984 • 444 citations

Purification, sequencing and synthesis of natriuretic and vasoactive rat atrial peptide

1984 • 434 citations

The role of humoral agents in volume expanded hypertension

1976 • 411 citations

Atrial natriuretic factor in rat hypothalamus, atria and plasma: Determination by specific radioimmunoassay

1984 • 362 citations

Effect of native and synthetic atrial natriuretic factor on cyclic GMP

1984 • 359 citations

Atriopeptin-Immunoreactive Neurons in the Brain: Presence in Cardiovascular Regulatory Areas

1985 • 355 citations

Release of atrial natriuretic peptide by atrial distension

1985 • 328 citations

Plasma levels of immunoreactive atrial natriuretic factor in healthy subjects and in patients with edema.

1985 • 324 citations

Atrial Natriuretic Factor Inhibits Dehydration and Hemorrhage-Induced Vasopressin Release

1985 • 318 citations

Cloning and sequence analysis of cDNA encoding a precursor for human atrial natriuretic poly peptide

1984 • 318 citations

Vasopressin-Stimulated Release of Atriopeptin: Endocrine Antagonists in Fluid Homeostasis

1985 • 314 citations

Ser-Leu-Arg-Arg-Atriopeptin III: The Major Circulating Form of Atrial Peptide

1985 • 310 citations

SPECIFIC RECEPTOR-MEDIATED INHIBITION BY SYNTHETIC ATRIAL NATRIURETIC FACTOR OF HORMONE-STIMULATED STEROIDOGENESIS IN CULTURED BOVINE ADRENAL CELLS.

1984 • 308 citations

Heart Atria Granularity Effects of Changes in Water-Electrolyte Balance

1979 • 301 citations

Atrial natriuretic factor: Structure and functional properties

1985 • 298 citations

Atrial natriuretic factor inhibits angiotensin-, norepinephrine-, and potassium-induced vascular contractility.

1984 • 294 citations

Atrial natriuretic factor (ANF) binding sites in brain and related structures

1984 • 293 citations

Radioautographic localization of125I-atrial natriuretic fator (ANF) in rat tissues

1985 • 289 citations

Rat atrial natriuretic factor: Complete amino acid sequence and disulfide linkage essential for biological activity

1984 • 281 citations

ATRIAL NATRIURETIC FACTOR INHIBITS THE STIMULATION OF ALDOSTERONE SECRETION BY ANGIOTENSIN II, ACTH AND POTASSIUMIN VITROAND ANGIOTENSIN II-INDUCED STEROIDOGENESISIN VIVO.

1984 • 271 citations

Immunocytochemical localization of atrial natriuretic factor in the heart and salivary glands

1984 • 267 citations

Specific membrane receptors for atrial natriuretic factor in renal and vascular tissues.

1984 • 263 citations

Cloning and sequence analysis of the cDNA for the rat atrial natriuretic factor precursor

1984 • 257 citations

Structure of rat atrial natriuretic factor precursor deduced from cDNA sequence

1984 • 251 citations

Actions of synthetic atrial natriuretic factor on bovine adrenal glomerulosa

1984 • 250 citations

Renal effects of head-out water immersion in man: implications for an understanding of volume homeostasis.

1978 • 244 citations

Renal mechanism of action of rat atrial natriuretic factor.

1985 • 242 citations

Cellular mechanism of release of atrial natriuretic factor

1984 • 233 citations

The Structure of Rat Preproatrial Natriuretic Factor as Defined by a Complementary DNA Clone

1984 • 233 citations

α-Human atrial natriuretic polypeptide is released from the heart and circulates in the body

1985 • 231 citations

The increase of cGMP by atrial natriuretic factor correlates with the distribution of particulate guanylate cyclase

1985 • 228 citations

The possible role of cardiac atrial stretch receptors in the induction of changes in urine flow

1956 • 227 citations

Evidence for the Existence of Atrial Natriuretic Factor-Containing Neurons in the Rat Brain

1985 • 226 citations

Inhibition of aldosterone production in the adrenal glomerulosa by atrial natriuretic factor

1984 • 221 citations

Intrarenal localization of the natriuretic effect of cardiac atrial extract

1982 • 220 citations

Vasodilator profile of synthetic atrial natriuretic factor

1984 • 214 citations

Identification of rat γ atrial natriuretic polypeptide and characterization of the cDNA encoding its precursor

1984 • 211 citations

Amino acid sequence of homologous rat atrial peptides: natriuretic activity of native and synthetic forms.

1984 • 210 citations

Structural identification of β- and γ-human atrial natriuretic polypeptides

1985 • 207 citations

Nucleotide Sequences of the Human and Mouse Atrial Natriuretic Factor Genes

1984 • 207 citations

Specific receptors for atrial natriuretic factor (ANF) in cultured vascular smooth muscle cells of rat aorta

1984 • 207 citations

Atrial natriuretic factor inhibits dehydration- and angiotensin II-induced water intake in the conscious, unrestrained rat.

1985 • 207 citations

Sodium transport inhibitor from bovine hypothalamus.

1979 • 194 citations

Characterization of specific receptors for atrial natriuretic factor in bovine adrenal zona glomerulosa

1984 • 192 citations

Failure of atriopeptin II to cause arterial vasodilation in the conscious rat.

1985 • 192 citations

Micropuncture studies of the renal effects of atrial natriuretic substance

1982 • 192 citations

mRNA sequence for human cardiodilatin–atrial natriuretic factor precursor and regulation of precursor mRNA in rat atria

1984 • 190 citations

The mechanism of cGMP-induced relaxation in vascular smooth muscle

1985 • 180 citations

Cardionatrin I — A novel heart peptide with potent diuretic and natriuretic properties

1983 • 180 citations

The effect of a natriuretic atrial extract on renal haemodynamics and urinary excretion in anaesthetized rats.

1983 • 174 citations

Relationship of specific granules to the natriuretic and diuretic activity of rat atria

1982 • 173 citations

Tissue fractionation studies on the relationship between an atrial natriuretic factor and specific atrial granules

1982 • 167 citations

Atrial natriuretic factor inhibits adenylate cyclase activity

1984 • 165 citations

Identification of a biologically active circulating form of rat atrial natriuretic factor

1985 • 162 citations

Atriopeptins: A family of potent biologically active peptides derived from mammalian atria

1984 • 159 citations

Rat atrial natriuretic factor. Purification and vasorelaxant activity

1983 • 158 citations

Atrial Natriuretic Factor of the Rat Heart. Studies on Isolation and Properties

1982 • 145 citations

The right auricle of the heart is an endocrine organ

1983 • 138 citations

Atrial receptors and renal function

1975 • 136 citations

Natriuretic activity in plasma and urine of salt-loaded man and sheep

1969 • 136 citations

Atrial natriuretic factor is a circulating hormone

1984 • 135 citations

Distinct atrial natriuretic factor receptor sites on cultured bovine aortic smooth muscle and endothelial cells

1985 • 135 citations

Cardiovascular effects of atrial extracts in anesthetized rats

1984 • 130 citations

Nucleotide sequence of the gene encoding human atrial natriuretic factor precursor

1984 • 129 citations

Influence of right and left atrial receptors on plasma concentrations of ADH and renin

1971 • 128 citations

An atrial peptide is a potent renal vasodilator substance.

1984 • 127 citations

Renal and systemic effects of synthetic atrial natriuretic factor

1985 • 124 citations

Antidipsogenic action of α-human atrial natriuretic polypeptide administered intracerebroventricularly in rats

1985 • 123 citations

Identification in rat atrial tissue of multiple forms of natriuretic polypeptides of about 3,000 daltons

1984 • 122 citations

Gene structure of human cardiac hormone precursor, pronatriodilatin

1984 • 120 citations

Alignment of Rat Cardionatrin Sequences with the Preprocardionatrin Sequence from Complementary DNA

1985 • 119 citations

Effect of Chronic Infusion of Synthetic Atrial Natriuretic Factor (ANF 8-33) in Conscious Two-Kidney, One-Clip Hypertensive Rats

1985 • 119 citations

Primary structure of a high M_r form of rat atrial natriuretic factor

1984 • 118 citations

Effect of atrial natriuretic factor (ANF)-related peptides on aldosterone secretion by adrenal glomerulosa cells: Critical role of the intramolecular disulphide bond

1984 • 116 citations

Vascular receptor binding activities and cyclic GMP responses by synthetic human and rat atrial natriuretic peptides (ANP) and receptor down-regulation by ANP

1985 • 112 citations

Inhibition of aldosterone biosynthesis by atriopeptins in rat adrenal cells.

1985 • 110 citations

Atrial natriuretic factor. Characterization and partial purification.

1983 • 109 citations

Rat atrial natriuretic factor: Isolation, structure and biological activities of four major peptides

1984 • 106 citations

POLYURIA IN PAROXYSMAL TACHYCARDIA AND PAROXYSMAL ATRIAL FLUTTER AND FIBRILLATION

1963 • 104 citations

Atrial natriuretic factor has a direct, prostaglandin-independent action on kidneys

1982 • 104 citations

Purification and complete amino acid sequence of beta-rat atrial natriuretic polypeptide (β-rANP) of 5,000 daltons

1984 • 103 citations

Chronic Infusion of Low Doses of Atrial Natriuretic Factor (ANF Arg 101-Tyr 126) Reduces Blood Pressure in Conscious SHR without Apparent Changes in Sodium Excretion

1985 • 101 citations

Inhibition of aldosterone production by α-human atrial natriuretic polypeptide is associated with an increase in cGMP production

1985 • 99 citations

Cardiac Atria of BIO 14.6 Hamsters Are Deficient in Natriuretic Factor

1984 • 98 citations

Structure-activity relationships of atrial natriuretic factor (ANF). I. Natriuretic activity and relaxation of intestinal smooth muscle

1984 • 97 citations

Atrial natriuretic factor: reduced cardiac content in spontaneously hypertensive rats.

1983 • 94 citations

Identification of a receptor for atrial natriuretic factor in rabbit aorta membranes by affinity cross-linking.

1985 • 93 citations

Photoaffinity labeling of atrial natriuretic factor receptors of rat kidney cortex plasma membranes.

1985 • 92 citations

Synthesis of atrial natriuretic peptides and studies on structural factors in tissue specificity

1984 • 88 citations

THE EFFECTS OF ATRIAL STRETCH ON ALDOSTERONE SECRETION¹

1959 • 88 citations

Comparative vascular pharmacology of the atriopeptins.

1985 • 86 citations

The role of left atrial receptors in the diuretic response to left atrial distension

1968 • 83 citations

Natriuretic and sodium transport inhibitory activity in plasma of volume-expanded dogs

1974 • 80 citations

Effects of atrial natriuretic factor on renal handling of water and electrolytes in rats

1983 • 80 citations

Purification of three rat atrial natriuretic factors and their amino acid composition

1983 • 78 citations

Inhibition of transepithelial sodium transport in the frog skin by a low molecular weight fraction of uremic serum

1971 • 77 citations

Photoaffinity labeling of atrial natriuretic factor receptor in bovine and rat adrenal cortical membranes

1985 • 77 citations

Renal and blood pressure responses to synthetic atrial natriuretic factor in spontaneously hypertensive rats.

1985 • 74 citations

Partial Chemical Characterization of a Natriuretic Substance in Rat Atrial Heart Tissue

1982 • 70 citations

Structure-activity relationships of atrial natriuretic factor (ANF). II. Effect of chain-length modifications on vascular reactivity

1985 • 70 citations

Isolation and sequence determination of peptide components of atrial natriuretic factor

1984 • 69 citations

Synthetic atrial natriuretic factor in conscious normotensive and hypertensive rats.

1985 • 62 citations

Control of plasma ADH titer in hemorrhage: role of atrial and arterial receptors

1968 • 61 citations

Atriopeptin release from the isolated perfused rabbit heart

1984 • 60 citations

Inhibitory effect of atrial natriuretic factor on adenylate cyclase activity in adrenal cortical membranes

1985 • 60 citations

Partially purified human and rat atrial natriuretic factor.

1983 • 60 citations

Solubilization and molecular weight estimation of atrial natriuretic factor receptor from bovine adrenal cortex

1985 • 58 citations

Kallikrein activation of a high molecular weight atrial peptide

1984 • 57 citations

Atrial natriuretic factor selectively increases renal blood flow in conscious spontaneously hypertensive rats

1984 • 56 citations

Synthetic Atrial Natriuretic Factor Induces Release (Possibly Receptor-Mediated) of Vasopressin from Rat Posterior Pituitary

1985 • 55 citations

Atrial natriuretic factor stimulates testosterone production by mouse interstitial cells

1985 • 54 citations

Atrial pronatriodilatin: a precursor for natriuretic factor and cardiodilatin

1984 • 53 citations

Natriuretic effect of atrial extract on isolated perfused rat kidney

1983 • 52 citations

The sequence of an atriopeptigen: A precursor of the bioactive atrial peptides

1984 • 51 citations

Atrial natriuretic factor in Dahl rats. Atrial content and renal and aortic responses.

1985 • 45 citations

Existence of atrial natriuretic polypeptide in kidney

1985 • 44 citations

Hypertension-producing factor in serum of hypertensive Dahl salt-sensitive rats.

1984 • 43 citations

Atrial reflexes and renal function

1979 • 42 citations

Cardionatrin causes vasodilation in vitro which is not dependent on the presence of endothelial cells

1984 • 42 citations

A Humoral Component of the Natriuretic Mechanism in Sustained Blood Volume Expansion

1972 • 39 citations

Atrial tissue contains a metallo dipeptidyl carboxyhydrolase not present in ventricular tissue: Partial purification and characterization

1984 • 36 citations

Differential structure-activity relationships of atrial peptides as natriuretics and renal vasodilators in the dog

1985 • 34 citations

Proteolytic activation of a bioactive cardiac peptide by in vitro trypsin cleavage.

1984 • 30 citations

Antihypertensive and aldosterone-lowering effects of synthetic atrial natriuretic factor in renin-dependent renovascular hypertension.

1984 • 27 citations

Renal responses to atrial natriuretic factor during converting enzyme inhibition

1985 • 13 citations

Deleted Work

1955 • 0 citations