The proteolysis-dependent metaphase to anaphase transition: calcium/calmodulin-dependent protein kinase II mediates onset of anaphase in extracts prepared from unfertilized Xenopus eggs.

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes

1971 • 1,553 citations

Cyclin synthesis drives the early embryonic cell cycle

1989 • 1,223 citations

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

1989 • 1,114 citations

Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination

1992 • 780 citations

Cyclin activation of p34cdc2

1990 • 690 citations

Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor

1993 • 569 citations

Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast.

1993 • 483 citations

Calmodulin-dependent protein kinase II mediates inactivation of MPF and CSF upon fertilization of Xenopus eggs

1993 • 437 citations

S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase

1993 • 422 citations

The inner centromere protein (INCENP) antigens: movement from inner centromere to midbody during mitosis.

1987 • 407 citations

Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells

1992 • 298 citations

Occurrence of a polyubiquitin structure in ubiquitin-protein conjugates

1985 • 263 citations

Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit

1993 • 244 citations

The requirements for protein synthesis and degradation, and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryo.

1992 • 236 citations

Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase cdc2.

1994 • 235 citations

Sister chromatid separation in frog egg extracts requires DNA topoisomerase II activity during anaphase

1992 • 235 citations

Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase

1990 • 222 citations

The ubiquitin‐mediated proteolytic pathway: mechanisms of recognition of the proteolytic substrate and involvement in the degradation of native cellular proteins

1994 • 199 citations

Phosphorylation of myosin-II regulatory light chain by cyclin-p34cdc2: a mechanism for the timing of cytokinesis.

1992 • 197 citations

Degradation of the proto-oncogene product p39mos is not necessary for cyclin proteolysis and exit from meiotic metaphase: requirement for a Ca(2+)-calmodulin dependent event.

1991 • 174 citations

Scanning electron microscopy of mammalian chromosomes from prophase to telophase

1991 • 173 citations

Degradation of Mos by the N-terminal proline (Pro2)-dependent ubiquitin pathway on fertilization of Xenopus eggs: possible significance of natural selection for Pro2 in Mos.

1993 • 127 citations

Cyclic activation of histone H1 kinase during sea urchin egg mitotic divisions

1988 • 126 citations

Control of M-phase by maturation-promoting factor

1990 • 111 citations

Calcium transients during mitosis: observations in flux.

1989 • 111 citations

Effects of Ca2+ ions on the formation of metaphase chromosomes and sperm pronuclei in cell-free preparations from unactivated Rana pipiens eggs

1984 • 90 citations

Detection of distinct structural domains within the primary constriction using autoantibodies

1988 • 81 citations

Spindle Fiber Action and Chromosome Movement

1991 • 62 citations

Towards understanding the control of the division cycle in animal cells

1992 • 62 citations

Microinjection of antibodies to a 62 kd mitotic apparatus protein arrests mitosis in dividing sea urchin embryos

1989 • 47 citations

A nuclear factor required for specific translation of cyclin B may control the timing of first meiotic cleavage in starfish oocytes.

1993 • 42 citations

Proteins of the inner and outer centromere of mitotic chromosomes

1989 • 29 citations