The regulation of thymidylate biosynthesis in Novikoff hepatoma cells and the effects of amethopterin, 5-fluorodeoxyuridine, and 3-deazauridine.

Statistical estimations in enzyme kinetics

1961 • 3,586 citations

The purine and pyrimidine composition of deoxypentose nucleic acids

1951 • 1,084 citations

The precision of ultraviolet absorption measurements in the Schmidt-Thannhauser procedure for nucleic acid estimation

1962 • 1,066 citations

Computer Programmes for Processing Enzyme Kinetic Data

1963 • 655 citations

THE MODE OF ACTION OF 5-FLUOROURACIL AND ITS DERIVATIVES

1958 • 634 citations

Enzymology of Cancer Cells

1977 • 420 citations

Regulation of Mammalian Deoxyribonucleotide Biosynthesis by Nucleotides as Activators and Inhibitors

1966 • 395 citations

Ribonucleotide Reductase and Cell Proliferation

1970 • 307 citations

Role of effector binding in allosteric control of ribonucleoside diphosphate reductase

1969 • 234 citations

Cytidine Triphosphate Synthetase of Escherichia coli B

1967 • 190 citations

Nucleotide Interconversions

1960 • 186 citations

A rapid quantitative determination of deoxyribonucleoside triphosphates based on the enzymatic synthesis of DNA

1969 • 157 citations

An Enzymatic Method for the Determination of dCTP and dGTP in Picomole Amounts

1970 • 140 citations

On the Nature of a Sparing Effect by Thymidine on the Utilization of Deoxycytidine^*

1962 • 126 citations

Enzymatic Synthesis of Deoxyribonucleotides

1966 • 125 citations

Replication of Mengovirus I. Effect on Synthesis of Macromolecules by Host Cell

1966 • 123 citations

A New Assay of Thymidylate Synthetase Activity Based on the Release of Tritium from Deoxyuridylate-5-3H

1967 • 122 citations

Altered deoxyribonucleotide pools in P2 eductants of Escherichia coli K-12 due to deletion of the dcd gene

1976 • 115 citations

The Purification and Properties of Deoxycytidylate Deaminase from Chick Embryo Extracts

1964 • 108 citations

Studies concerning inhibition of the synthesis of deoxycytidine by phosphorylated derivatives of thymidine

1960 • 102 citations

Pyrimidine Nucleotide Metabolism and Pathways of Thymidine Triphosphate Biosynthesis in Salmonella typhimurium

1968 • 92 citations

Inhibition of thymidine kinase activity in liver and hepatomas by TTP and d-CTP

1964 • 86 citations

Factors determining cell sensitivity to methotrexate: Studies of folate and deoxyribonucleoside triphosphate pools in five mammalian cell lines

1974 • 84 citations

The effect of methotrexate on enzymes induced following partial hepatectomy.

1969 • 83 citations

Inhibiyors of protein synthesis: Effect on the levels of deoxycytidylate deaminase, thymidylate synthetase, and thymidine kinase in regenerating rat liver

1965 • 78 citations

Combination chemotherapy: The interaction of methotrexate and 5-fluorouracil

1973 • 74 citations

The mechanism of action of methotrexate. I. Interaction with a low-affinity intracellular site required for maximum inhibition of deoxyribonucleic acid synthesis in L-cell mouse fibroblasts.

1974 • 74 citations

The Enzymatic Aminohydrolysis of 4-Aminopyrimidine Deoxyribonucleotides

1963 • 71 citations

Enzymes of thymidine triphosphate synthesis in selected Morris hepatomas.

1969 • 66 citations

Deoxycytidine Triphosphate Deaminase: Characterization of an Escherichia coli Mutant Deficient in the Enzyme

1971 • 61 citations

The effect of external deoxyribonucleosides on deoxyribonucleoside triphosphate concentrations in human lymphocytes

1975 • 58 citations

Nucleotide Interconversions

1962 • 56 citations

The pool size of deoxyguanosine 5′-triphosphate and deoxycytidine 5′-triphosphate in phytohemagglutinin-stimulated and non-stimulated human lymphocytes

1975 • 52 citations

Inhibition of growth rate and deoxynucleoside triphosphate concentrations in cultured leukemia L1210 cells.

1976 • 51 citations

Deoxycytidine Triphosphate Deaminase: Identification and Function in Salmonella typhimurium

1971 • 47 citations

Purification of Thymidylate Synthetase from Ehrlich Ascites Carcinoma Cells

1971 • 41 citations

Ordered and specific pattern of gene expression in neoplasia

1973 • 38 citations

Effect of methotrexate and 5-fluorodeoxyuridine on ribonucleotide reductase activity in mammalian cells.

1977 • 38 citations

Purification and properties of deoxythymidine kinases from the Yoshida sarcoma.

1972 • 34 citations

The Enzymatic Deamination of 6-Aminopyrimidine Deoxyribonucleotides

1960 • 34 citations

[21] Mammalian ribonucleoside diphosphate reductases

1967 • 30 citations

Characterization of pyrimidine nucleoside monophosphokinase in normal and malignant tissues.

1977 • 16 citations

Differences between pyrimidine nucleoside monophosphate kinase from rat Novikoff ascites hepatoma and rat liver.

1976 • 10 citations